Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | CASR | P41180 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2016076 | 0.90 | MEN1 (0.50) | MEN1KMT2ATP53ALDH1A1SMN1; SMN2 | |
| SCHEMBL2018696 | 0.90 | MEN1 (0.65) | MEN1KMT2ATP53ALDH1A1SMN1; SMN2 | |
| SCHEMBL2015349 | 0.88 | HTT (0.57) | MEN1KMT2ATP53SMN1; SMN2LMNA | |
| SCHEMBL2014088 | 0.86 | LMNA (0.65) | MEN1KMT2ATP53SMN1; SMN2LMNA | |
| SCHEMBL2016412 | 0.85 | TP53 (0.56) | MEN1KMT2ATP53ALDH1A1SMN1; SMN2 | |
| SCHEMBL12635944 | 0.82 | SCNN1A (0.39) | ALDH1A1SMN1; SMN2LMNAHPGDRAB9A | |
| Iodide SCHEMBL2015549 | 0.81 | SCNN1A (0.39) | ALDH1A1SMN1; SMN2LMNAHPGDRAB9A | |
| SCHEMBL2018051 | 0.81 | TP53 (0.45) | MEN1KMT2ATP53SMN1; SMN2LMNA | |
| SCHEMBL12636626 | 0.77 | L3MBTL1 (0.55) | MEN1KMT2ATP53ALDH1A1SMN1; SMN2 | |
| SCHEMBL2051754 | 0.77 | MEN1 (0.64) | MEN1KMT2ATP53ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011079087-A1 | ENAC BLOCKERS | GLAXO GROUP LIMITED (GB) | 2011-06-30 | — | — | WO | disclosed |
| WO-2011079087-A1 | ENAC BLOCKERS | GLAXO GROUP LIMITED (GB) | 2011-06-30 | — | — | WO | disclosed |