Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.34 |
| ▸ | HPGD | P15428 | 5/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 5/20 | 0.34 |
| ▸ | HTR2C | P28335 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.30 |
| ▸ | TUBB | P07437 | 2/20 | 0.30 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.30 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.30 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.30 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.30 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.30 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1494400 | 0.75 | KDM4E (0.57) | ALDH1A1KDM4EHPGDGAANPSR1 | |
| SCHEMBL1494524 | 0.72 | ALDH1A1 (0.46) | ALDH1A1KDM4EHPGDGAANPSR1 | |
| SCHEMBL10605443 | 0.69 | ALOX5 (0.57) | ALDH1A1KDM4EHPGDHTR2AHTR2C | |
| SCHEMBL5803546 | 0.68 | KDM4E (0.54) | ALDH1A1KDM4EHPGDGAANPSR1 | |
| SCHEMBL12255348 | 0.66 | AKR1C2 (0.56) | ALDH1A1KDM4EHPGDGAANPSR1 | |
| SCHEMBL12255237 | 0.65 | MTNR1A (0.46) | ALDH1A1KDM4EHPGDGAANPSR1 | |
| SCHEMBL1494152 | 0.64 | HTR2A (0.40) | ALDH1A1KDM4EHPGDNPSR1HTR2A | |
| SCHEMBL20756625 | 0.62 | HTR2A (0.62) | ALDH1A1HPGDHTR2AHTR2CLMNA | |
| SCHEMBL21676217 | 0.61 | GRIN2D (0.66) | ALDH1A1KDM4EHPGDGAAHTR2A | |
| SCHEMBL8805636 | 0.61 | LMNA (0.44) | ALDH1A1KDM4EHPGDGAANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180141919-A1 | DIAMINOPYRIMIDINES AS P2X3 AND P2X2/3 ANTAGONISTS | ROCHE PALO ALTO LLC (US) | 2018-05-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180141919-A1 | DIAMINOPYRIMIDINES AS P2X3 AND P2X2/3 ANTAGONISTS | P2RX3, P2RX6, P2RX2 | ALDH1A1 2017/4885KDM4E 3345/4885HPGD 814/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.