SCHEMBL20183978

SCHEMBL20183978

C=CC(=O)Oc1ccc(N=C=S)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 4/20 0.47
HSD17B10 Q99714 3/20 0.42
P2RY6 Q15077 3/20 0.41
MIF P14174 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
RAD1 O60671 1/20 0.37
ELANE P08246 1/20 0.36
KDM4E B2RXH2 2/20 0.34
USP2 O75604 2/20 0.34
ALDH1A1 P00352 2/20 0.34
LTA P01374 2/20 0.34
CYP3A4 P08684 2/20 0.34
MAPT P10636 2/20 0.34
HPGD P15428 2/20 0.34
P2RX3 P56373 2/20 0.34
RAD51 Q06609 2/20 0.34
TDP1 Q9NUW8 2/20 0.34
F2 P00734 1/20 0.34
PRSS1 P07477 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL632538 0.86 THRB (0.47) THRBELANECYP3A4TDP1F2
SCHEMBL20183951 0.82 MIF (0.39) THRBHSD17B10P2RY6MIFRAD1
SCHEMBL14690375 0.81 ELANE (0.53) THRBELANEMAPTTDP1F2
SCHEMBL12312099 0.81 ELANE (0.53) THRBELANEMAPTTDP1F2
SCHEMBL2587522 0.80 THRB (0.64) THRBHSD17B10ELANEKDM4EALDH1A1
SCHEMBL14749524 0.79 THRB (0.51) THRBHSD17B10ELANEALDH1A1MAPT
SCHEMBL3419623 0.78 LMNA (0.53) HSD17B10P2RY6MIFCA1CA2
SCHEMBL28938218 0.78 THRB (0.50) THRBELANEMAPTF2PRSS1
SCHEMBL26079300 0.78 THRB (0.41) THRBHSD17B10P2RY6MIFCA1
SCHEMBL11779514 0.77 GAA (0.44) HSD17B10P2RY6ALDH1A1MAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10647784-B2 Resin and surface protective plate or automotive material SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2020-05-12 US disclosed
EP-3327052-B1 RESIN AND SURFACE PROTECTION PLATE OR AUTOMOTIVE MATERIAL SUMITOMO CHEMICAL CO (JP) 2020-03-04 EP disclosed
CN-107849199-B Resin, surface protective plate, or automobile material 住友化学株式会社 2019-12-27 CN disclosed
US-20180215837-A1 RESIN AND SURFACE PROTECTIVE PLATE OR AUTOMOTIVE MATERIAL SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-08-02 US disclosed
EP-3327052-A1 RESIN AND SURFACE PROTECTION PLATE OR AUTOMOTIVE MATERIAL Sumitomo Chemical Company, Ltd. (JP) 2018-05-30 EP disclosed
CN-107849199-A Resin and surface protection board or materials used in auto manufacturing 住友化学株式会社 2018-03-27 CN disclosed