Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | RET | P07949 | 2/20 | 0.47 |
| ▸ | PLK4 | O00444 | 1/20 | 0.47 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.47 |
| ▸ | AURKA | O14965 | 1/20 | 0.47 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.47 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.47 |
| ▸ | CSF1R | P07333 | 1/20 | 0.47 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.47 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.47 |
| ▸ | LTK | P29376 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.47 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.47 |
| ▸ | FLT3 | P36888 | 1/20 | 0.47 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5483794 | 0.76 | HPGD (0.62) | NOS1KDM4EHPGDHSD17B10TDP1 | |
| SCHEMBL731908 | 0.74 | NOS1 (0.53) | NOS1KDM4EHPGDHSD17B10TDP1 | |
| SCHEMBL29935737 | 0.74 | NOS1 (0.53) | NOS1KDM4EHPGDHSD17B10TDP1 | |
| SCHEMBL5054128 | 0.74 | PLK4 (0.54) | NOS1KDM4EHPGDHSD17B10TDP1 | |
| SCHEMBL20184100 | 0.74 | NOS1 (0.49) | NOS1KDM4EHPGDCYP1A2CYP3A4 | |
| SCHEMBL30539134 | 0.72 | PLK4 (0.61) | NOS1KDM4EHPGDHSD17B10TDP1 | |
| SCHEMBL27784126 | 0.72 | PLK4 (0.53) | NOS1KDM4EHPGDHSD17B10TDP1 | |
| SCHEMBL30788421 | 0.71 | NOS1 (0.50) | NOS1KDM4EHPGDHSD17B10TDP1 | |
| SCHEMBL15505902 | 0.71 | NOS1 (0.50) | NOS1KDM4EHPGDHSD17B10TDP1 | |
| SCHEMBL29520821 | 0.71 | TRPA1 (0.51) | NOS1KDM4EHPGDHSD17B10TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3325486-A1 | POLYNITROGEN COMPOUNDS AND USES THEREOF AS FLUORESCENT CHROMOPHORES | Universite D'Orleans (FR) | 2018-05-30 | — | — | EP | disclosed |