⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7839776 | 0.74 | HSD17B1 (0.46) | — | |
| SCHEMBL8523642 | 0.68 | — | — | |
| SCHEMBL8795485 | 0.67 | LMNA (0.39) | — | |
| SCHEMBL7840064 | 0.64 | CYP2D6 (0.38) | — | |
| SCHEMBL3990520 | 0.63 | ALOX5 (0.46) | — | |
| SCHEMBL8102074 | 0.63 | ESR1 (0.50) | — | |
| SCHEMBL27532615 | 0.62 | SRC (0.36) | — | |
| SCHEMBL7794439 | 0.62 | ALOX5 (0.50) | — | |
| SCHEMBL7762847 | 0.62 | — | — | |
| SCHEMBL8684452 | 0.61 | LMNA (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115916774-A | Process for the preparation of fluoxastrobin and intermediates thereof | UPL有限公司 | 2023-04-04 | — | — | CN | disclosed |
| CN-113825744-A | Process for preparing fungicidally active strobilurin compounds and intermediates thereof | UPL有限公司 | 2021-12-21 | — | — | CN | disclosed |
| US-20180148423-A1 | Process for Preparing (E)-(5,6-Dihydro-1,4,2-Dioxazine-3-YL) (2-Hydroxyphenyl) Methanone O-Methyl Oxime | ARYSTA LIFESCIENCE CORPORATION (JP) | 2018-05-31 | — | — | US | disclosed |