Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 9/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | GPR34 | Q9UPC5 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | MME | P08473 | 10/20 | 0.47 |
| ▸ | CPA1 | P15085 | 7/20 | 0.47 |
| ▸ | ACE2 | Q9BYF1 | 7/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18229007 | 1.00 | ACE (0.52) | ACEALDH1A1GPR34CA2MME | |
| SCHEMBL18229004 | 0.86 | GPR34 (0.56) | ACEALDH1A1GPR34MMECPA1 | |
| SCHEMBL28681245 | 0.86 | GPR34 (0.56) | ACEALDH1A1GPR34MMECPA1 | |
| SCHEMBL20187246 | 0.84 | CA2 (0.49) | ACEALDH1A1GPR34CA2MME | |
| SCHEMBL18228976 | 0.84 | CA2 (0.49) | ACEALDH1A1GPR34CA2MME | |
| SCHEMBL18228990 | 0.83 | ACE (0.52) | ACEALDH1A1GPR34CA2MME | |
| SCHEMBL18228972 | 0.83 | CTSS (0.50) | ACEALDH1A1GPR34CA2MME | |
| SCHEMBL18229003 | 0.80 | MME (0.49) | ACEALDH1A1GPR34CA2MME | |
| SCHEMBL20187263 | 0.79 | CTSS (0.66) | ACE | |
| SCHEMBL18228975 | 0.79 | CTSS (0.66) | ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10287316-B2 | Process for preparation of nitrogen mustard derivatives | ONCOPEPTIDES AB (SE) | 2019-05-14 | — | — | US | disclosed |
| US-20180148473-A1 | PROCESS FOR PREPARATION OF NITROGEN MUSTARD DERIVATIVES | ONCOPEPTIDES AB (SE) | 2018-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180148473-A1 | PROCESS FOR PREPARATION OF NITROGEN MUSTARD DERIVATIVES | CBR3, GRHPR, CTH | ACE 1077/4885ALDH1A1 1092/4885GPR34 3963/4885 |
| US-10287316-B2 | Process for preparation of nitrogen mustard derivatives | CBR3, GRHPR, CTH | ACE 1077/4885ALDH1A1 1092/4885GPR34 3963/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.