Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.76 |
| ▸ | TAS1R3 | Q7RTX0 | 6/20 | 0.63 |
| ▸ | TAS1R1 | Q7RTX1 | 6/20 | 0.63 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | FNTA | P49354 | 2/20 | 0.48 |
| ▸ | FNTB | P49356 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 3/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | PLK1 | P53350 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL201891 | 1.00 | L3MBTL1 (0.76) | L3MBTL1TAS1R3TAS1R1GAAHTT | |
| SCHEMBL203604 | 0.89 | TAS1R3 (0.67) | L3MBTL1TAS1R3TAS1R1GAAPLK1 | |
| SCHEMBL203603 | 0.89 | TAS1R3 (0.67) | L3MBTL1TAS1R3TAS1R1GAAPLK1 | |
| SCHEMBL201285 | 0.88 | CA2 (0.60) | L3MBTL1TAS1R3TAS1R1FNTAFNTB | |
| SCHEMBL28736821 | 0.87 | L3MBTL1 (1.00) | L3MBTL1TAS1R3TAS1R1GAAHTT | |
| SCHEMBL203577 | 0.86 | L3MBTL1 (0.56) | L3MBTL1TAS1R3TAS1R1KMT2ACA2 | |
| SCHEMBL203576 | 0.86 | L3MBTL1 (0.56) | L3MBTL1TAS1R3TAS1R1KMT2ACA2 | |
| SCHEMBL200816 | 0.84 | TAS1R3 (0.63) | L3MBTL1TAS1R3TAS1R1GAACA2 | |
| SCHEMBL201947 | 0.83 | TAS1R3 (0.69) | L3MBTL1TAS1R3TAS1R1GAAPLK1 | |
| SCHEMBL8106910 | 0.80 | L3MBTL1 (0.74) | L3MBTL1TAS1R3TAS1R1GAAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8088804-B2 | N-hydroxyamide derivatives possessing antibacterial activity | PFIZER INC. (US) | 2012-01-03 | — | — | US | disclosed |
| EP-2338878-A2 | N-hydroxyamide derivatives possessing antibacterial activity | Vicuron Pharmaceuticals, Inc. (US) | 2011-06-29 | — | — | EP | disclosed |
| US-20100022605-A1 | N-HYDROXYAMIDE DERIVATIVES POSSESSING ANTIBACTERIAL ACTIVITY | VICURON PHARMACEUTICALS INC. | 2010-01-28 | — | — | US | disclosed |
| EP-1963262-A2 | N-HYDROXYAMIDE DERIVATIVES POSSESSING ANTIBACTERIAL ACTIVITY | Vicuron Pharmaceuticals, Inc. (US) | 2008-09-03 | — | — | EP | disclosed |
| WO-2007069020-A2 | N-HYDROXYAMIDE DERIVATIVES POSSESSING ANTIBACTERIAL ACTIVITY | VICURON PHARMACEUTICALS INC. (US) | 2007-06-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100022605-A1 | N-HYDROXYAMIDE DERIVATIVES POSSESSING ANTIBACTERIAL ACTIVITY | NAAA, HDHD5, HACL2 | L3MBTL1 2179/4885TAS1R3 1250/4885TAS1R1 1011/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.