Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | GPR174 | Q9BXC1 | 1/20 | 0.39 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 6/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8010476 | 0.84 | CHRNB2 (0.49) | MEN1KMT2AALDH1A1POLBPKM | |
| SCHEMBL3566984 | 0.83 | KMT2A (0.47) | MEN1KMT2AALDH1A1POLBPKM | |
| SCHEMBL2608055 | 0.81 | PTPN7 (0.63) | MEN1KMT2AALDH1A1L3MBTL1PTPN7 | |
| SCHEMBL2608056 | 0.80 | PTGS2 (0.57) | MEN1KMT2AALDH1A1HTR2CPTPN7 | |
| SCHEMBL14957533 | 0.80 | KMT2A (0.51) | MEN1KMT2AALDH1A1POLBPKM | |
| SCHEMBL30276927 | 0.80 | PTPN7 (0.61) | MEN1KMT2AALDH1A1POLBGPR174 | |
| SCHEMBL8430491 | 0.80 | PTPN7 (0.61) | MEN1KMT2AALDH1A1POLBGPR174 | |
| SCHEMBL3625535 | 0.80 | RELA (0.50) | MEN1KMT2AALDH1A1MAPTNPSR1 | |
| SCHEMBL10204628 | 0.77 | CA1 (0.46) | ALDH1A1MAPK1KDM4ERECQLCHRNB2 | |
| SCHEMBL283100 | 0.77 | TRPA1 (0.39) | HTR2CMAPTTRPA1CHRNB2CHRNB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9982194-B2 | Liquid-crystalline media | MERECK PATENT GMBH (DE) | 2018-05-29 | — | — | US | disclosed |