SCHEMBL20194003

SCHEMBL20194003

CSc1c[nH]c(C(C)C)n1

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6545978 0.80
SCHEMBL3322875 0.70
SCHEMBL786437 0.70 NOS3 (0.31)
SCHEMBL8528797 0.69
SCHEMBL8528800 0.69
Hydrochloric Acid SCHEMBL28150542 0.68 NOS3 (0.30)
SCHEMBL13034847 0.68
SCHEMBL4616815 0.68
Ammonia Solution, Strong SCHEMBL28135320 0.68 NOS3 (0.30)
SCHEMBL18595029 0.68

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200255413-A1 ANTIBACTERIAL COMPOUNDS BLACKSMITH MEDICINES, INC. 2020-08-13 US disclosed
US-20200188536-A1 CHLOROTOXIN CONJUGATES AND METHODS OF USE THEREOF Blaze Bioscience, Inc. 2020-06-18 US disclosed
US-20190225628-A1 BETA-LACTAMASE INHIBITORS NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2019-07-25 US disclosed
US-9981930-B1 MAGL inhibitors ABIDE THERAPEUTICS, INC. (US) 2018-05-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190225628-A1 BETA-LACTAMASE INHIBITORS MGAM, GAA, LCT MAPT 4167/4885
US-20200255413-A1 ANTIBACTERIAL COMPOUNDS SPOUT1, MRPL21, NRDC MAPT 2641/4885
US-20200188536-A1 CHLOROTOXIN CONJUGATES AND METHODS OF USE THEREOF CHLSN, QPCT, CBX6 MAPT 3357/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.