Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA5 | P31644 | 1/20 | 0.43 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
| ▸ | GRM5 | P41594 | 3/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | MPO | P05164 | 1/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22037240 | 0.86 | HTR7 (0.48) | SMN1; SMN2NR1H4HTR7MPO | |
| SCHEMBL22038672 | 0.80 | SMN1; SMN2 (0.43) | SMN1; SMN2HTR7GRM5KMT2ARAB9A | |
| SCHEMBL20195484 | 0.78 | GABRA5 (0.39) | GABRA5NR1H4HTR7GRM5RXRA | |
| SCHEMBL20686713 | 0.77 | SMN1; SMN2 (0.45) | SMN1; SMN2NPSR1NR1H4KMT2ANPC1 | |
| SCHEMBL22037695 | 0.75 | HTR7 (0.36) | GABRA5SMN1; SMN2HTR7 | |
| SCHEMBL22563957 | 0.74 | MAPT (0.40) | SMN1; SMN2NPSR1NR1H4KMT2A | |
| SCHEMBL22038196 | 0.74 | HTR7 (0.49) | GABRA5HTR7 | |
| SCHEMBL20686709 | 0.74 | MRGPRX4 (0.46) | SMN1; SMN2NPSR1KMT2ANPC1RAB9A | |
| SCHEMBL20195622 | 0.74 | GABRA5 (0.46) | GABRA5NR1H4CYP11B1CYP11B2KMT2A | |
| SCHEMBL20195624 | 0.74 | GABRA5 (0.43) | GABRA5BDKRB2SMN1; SMN2NPSR1CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3029035-B1 | TETRAZOLINONE COMPOUND, AND USE THEREOF | SUMITOMO CHEMICAL CO (JP) | 2018-05-30 | — | — | EP | disclosed |