SCHEMBL20195484

SCHEMBL20195484

Cc1cccc(OCc2c(SC(F)(F)F)cccc2N(C)N)n1

nearest known ligand 0.39

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
GABRA5 P31644 1/20 0.39
RXRA P19793 4/20 0.35
GRIN1 Q05586 4/20 0.35
GRIN2B Q13224 4/20 0.35
GRM5 P41594 1/20 0.31
HTR7 P34969 1/20 0.30
NR1H4 Q96RI1 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20195490 0.79 FFAR1 (0.30)
SCHEMBL20195403 0.78 GABRA5 (0.43) GABRA5RXRAGRIN1GRIN2BGRM5
SCHEMBL22038196 0.69 HTR7 (0.49) GABRA5HTR7
SCHEMBL20195661 0.67 RXRA (0.39) GABRA5RXRAGRIN1GRIN2BGRM5
SCHEMBL20195408 0.67 CYP11B1 (0.33) GABRA5RXRAGRIN1GRIN2BGRM5
SCHEMBL22037215 0.66 HTR7 (0.45) GABRA5HTR7
SCHEMBL20195407 0.66 HTR7 (0.32) HTR7
SCHEMBL22038690 0.66 HTR7 (0.43) GABRA5GRM5HTR7
SCHEMBL22037695 0.65 HTR7 (0.36) GABRA5HTR7
SCHEMBL22037240 0.65 HTR7 (0.48) HTR7NR1H4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3029035-B1 TETRAZOLINONE COMPOUND, AND USE THEREOF SUMITOMO CHEMICAL CO (JP) 2018-05-30 EP disclosed