Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA5 | P31644 | 1/20 | 0.46 |
| ▸ | SORT1 | Q99523 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | DHODH | Q02127 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TTR | P02766 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20195624 | 0.90 | GABRA5 (0.43) | GABRA5NPC1RAB9AKMT2AALDH1A1 | |
| SCHEMBL20195590 | 0.82 | GABRA5 (0.44) | GABRA5TP53HTTTSHRMRGPRX4 | |
| SCHEMBL20195623 | 0.82 | MCL1 (0.42) | SORT1TP53HTTTSHRMRGPRX4 | |
| SCHEMBL20195599 | 0.80 | GABRA5 (0.43) | GABRA5NR1H4 | |
| SCHEMBL20195519 | 0.75 | LMNA (0.46) | GABRA5HTTNPC1KMT2AALDH1A1 | |
| SCHEMBL18504615 | 0.75 | NR1H4 (0.43) | TP53HTTTSHRMRGPRX4ALDH1A1 | |
| SCHEMBL16920930 | 0.75 | MRGPRX4 (0.49) | TP53HTTMRGPRX4NPC1RAB9A | |
| SCHEMBL22564462 | 0.74 | NR1H4 (0.42) | TP53HTTTSHRMRGPRX4ALDH1A1 | |
| SCHEMBL20195626 | 0.74 | GABRA5 (0.42) | GABRA5NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL20195403 | 0.74 | GABRA5 (0.43) | GABRA5NPC1RAB9AKMT2ACYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3029035-B1 | TETRAZOLINONE COMPOUND, AND USE THEREOF | SUMITOMO CHEMICAL CO (JP) | 2018-05-30 | — | — | EP | disclosed |