Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 5/20 | 0.39 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20195513 | 0.79 | TAAR1 (0.34) | MAPTNFE2L2SLC22A12HTR1ASLC6A2 | |
| SCHEMBL20195504 | 0.73 | GRM5 (0.36) | MAPTADORA2ASLC6A2ALDH1A1 | |
| SCHEMBL20195581 | 0.72 | KMT2A (0.38) | CYP1A2CYP2C9CYP2C19SSTR4ALDH1A1 | |
| SCHEMBL20195545 | 0.72 | AOC3 (0.33) | — | |
| SCHEMBL20195515 | 0.71 | NPC1 (0.38) | MAPTCYP1A2CYP3A4CYP2D6TSHR | |
| SCHEMBL20195490 | 0.70 | FFAR1 (0.30) | SSTR4 | |
| SCHEMBL30440802 | 0.69 | SLC22A12 (0.55) | MAPTNFE2L2SLC22A12HTR1ASLC6A2 | |
| SCHEMBL322870 | 0.69 | SLC22A12 (0.55) | MAPTNFE2L2SLC22A12HTR1ASLC6A2 | |
| SCHEMBL20195505 | 0.69 | ADRA2A (0.33) | MAPTSLC6A2SLC6A4SLC6A3MAPK1 | |
| SCHEMBL22037259 | 0.69 | HTR7 (0.47) | HTR1AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3029035-B1 | TETRAZOLINONE COMPOUND, AND USE THEREOF | SUMITOMO CHEMICAL CO (JP) | 2018-05-30 | — | — | EP | disclosed |