SCHEMBL20195490

SCHEMBL20195490

Cc1cccnc1OCc1c(SC(F)(F)F)cccc1N(C)N

nearest known ligand 0.30

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 2/20 0.30
FFAR4 Q5NUL3 2/20 0.30
SSTR4 P31391 1/20 0.30
PDK2 Q15119 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20195484 0.79 GABRA5 (0.39)
SCHEMBL20195500 0.78 HTT (0.33) SSTR4
SCHEMBL20195504 0.77 GRM5 (0.36)
SCHEMBL20195406 0.70 MAPT (0.40) SSTR4
SCHEMBL20195513 0.69 TAAR1 (0.34) SSTR4
SCHEMBL20195461 0.69 CYP1A2 (0.33)
SCHEMBL20195620 0.68 KMT2A (0.32)
SCHEMBL20195450 0.68 HDAC1 (0.38)
SCHEMBL20195473 0.67 L3MBTL1 (0.33)
SCHEMBL20195570 0.65 TAAR1 (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3029035-B1 TETRAZOLINONE COMPOUND, AND USE THEREOF SUMITOMO CHEMICAL CO (JP) 2018-05-30 EP disclosed