Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20195505 | 0.86 | ADRA2A (0.33) | GRM5ALDH1A1LMNAHTTKMT2A | |
| SCHEMBL20195625 | 0.86 | NPC1 (0.38) | GRM5ALDH1A1LMNAALOX12HTT | |
| SCHEMBL20195500 | 0.84 | HTT (0.33) | LMNAHTTKMT2AL3MBTL1SGMS2 | |
| SCHEMBL20195451 | 0.82 | ALDH1A1 (0.45) | GRM5ALDH1A1LMNAALOX12HTT | |
| SCHEMBL20195561 | 0.80 | GABRA5 (0.39) | GRM5ALDH1A1KMT2AL3MBTL1ADRA2A | |
| SCHEMBL20195490 | 0.77 | FFAR1 (0.30) | — | |
| SCHEMBL18831599 | 0.77 | MRGPRX4 (0.41) | ALDH1A1LMNAHTTKMT2AL3MBTL1 | |
| SCHEMBL20195598 | 0.76 | KMT2A (0.49) | ALDH1A1HTTKMT2AL3MBTL1SGMS2 | |
| SCHEMBL20195552 | 0.75 | ALDH1A1 (0.43) | ALDH1A1LMNAHTTKMT2AL3MBTL1 | |
| SCHEMBL20195434 | 0.75 | ALDH1A1 (0.50) | ALDH1A1LMNAKMT2AL3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3029035-B1 | TETRAZOLINONE COMPOUND, AND USE THEREOF | SUMITOMO CHEMICAL CO (JP) | 2018-05-30 | — | — | EP | disclosed |