Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 1/20 | 0.32 |
| ▸ | GUCY1B2 | O75343 | 1/20 | 0.31 |
| ▸ | GUCY1A2 | P33402 | 1/20 | 0.31 |
| ▸ | GUCY1A1 | Q02108 | 1/20 | 0.31 |
| ▸ | GUCY1B1 | Q02153 | 1/20 | 0.31 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20195499 | 0.80 | GABRA5 (0.47) | — | |
| SCHEMBL20195408 | 0.72 | CYP11B1 (0.33) | HTR7 | |
| SCHEMBL22038196 | 0.71 | HTR7 (0.49) | HTR7 | |
| SCHEMBL20195620 | 0.71 | KMT2A (0.32) | GUCY1B2GUCY1A2GUCY1A1GUCY1B1 | |
| SCHEMBL22037240 | 0.70 | HTR7 (0.48) | HTR7 | |
| SCHEMBL20195412 | 0.69 | NR1H4 (0.32) | — | |
| SCHEMBL22038783 | 0.69 | HTR7 (0.47) | HTR7 | |
| SCHEMBL22037259 | 0.69 | HTR7 (0.47) | HTR7 | |
| SCHEMBL20195414 | 0.69 | TDP1 (0.41) | — | |
| SCHEMBL18831542 | 0.69 | KDM4E (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3029035-B1 | TETRAZOLINONE COMPOUND, AND USE THEREOF | SUMITOMO CHEMICAL CO (JP) | 2018-05-30 | — | — | EP | disclosed |