Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA5 | P31644 | 1/20 | 0.47 |
| ▸ | ALOX5AP | P20292 | 4/20 | 0.36 |
| ▸ | FEN1 | P39748 | 4/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CTSS | P25774 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20195407 | 0.80 | HTR7 (0.32) | — | |
| SCHEMBL20195408 | 0.71 | CYP11B1 (0.33) | GABRA5CYP11B1CYP11B2 | |
| SCHEMBL22037502 | 0.70 | HTR7 (0.41) | GABRA5GAA | |
| SCHEMBL20195620 | 0.70 | KMT2A (0.32) | GAAKDM4ERAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL20195414 | 0.68 | TDP1 (0.41) | KDM4ERAB9ASMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL18831542 | 0.68 | KDM4E (0.40) | GAAKDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL2952806 | 0.68 | GABRA5 (0.49) | GABRA5GAACTSSP2RX3 | |
| SCHEMBL22037223 | 0.68 | HTR7 (0.41) | GABRA5 | |
| SCHEMBL2959124 | 0.68 | GABRA5 (0.55) | GABRA5KDM4ERAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL22038196 | 0.68 | HTR7 (0.49) | GABRA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3029035-B1 | TETRAZOLINONE COMPOUND, AND USE THEREOF | SUMITOMO CHEMICAL CO (JP) | 2018-05-30 | — | — | EP | disclosed |