SCHEMBL20195450

SCHEMBL20195450

Cc1ccnnc1OCc1c(F)cccc1N(C)N

nearest known ligand 0.38

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
HDAC1 Q13547 1/20 0.38
HDAC6 Q9UBN7 1/20 0.38
HDAC5 Q9UQL6 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20195620 0.81 KMT2A (0.32)
SCHEMBL20195414 0.72 TDP1 (0.41)
SCHEMBL18831566 0.72 MRGPRX4 (0.37)
SCHEMBL20195461 0.69 CYP1A2 (0.33)
SCHEMBL20195500 0.69 HTT (0.33)
SCHEMBL20195504 0.68 GRM5 (0.36)
SCHEMBL20195407 0.68 HTR7 (0.32)
SCHEMBL20195490 0.68 FFAR1 (0.30)
SCHEMBL20195499 0.68 GABRA5 (0.47)
SCHEMBL20195545 0.68 AOC3 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3029035-B1 TETRAZOLINONE COMPOUND, AND USE THEREOF SUMITOMO CHEMICAL CO (JP) 2018-05-30 EP disclosed