Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | CSF1R | P07333 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | NOS3 | P29474 | 1/20 | 0.39 |
| ▸ | NOS1 | P29475 | 1/20 | 0.39 |
| ▸ | NOS2 | P35228 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CASP6 | P55212 | 1/20 | 0.36 |
| ▸ | MET | P08581 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20195568 | 0.82 | SYK (0.41) | SMN1; SMN2ALDH1A1KMT2ANOS3NOS1 | |
| SCHEMBL20195594 | 0.82 | BDKRB2 (0.43) | SMN1; SMN2ALDH1A1KMT2ACSF1RGAA | |
| SCHEMBL20195451 | 0.81 | ALDH1A1 (0.45) | SMN1; SMN2ALDH1A1KMT2AL3MBTL1NOS3 | |
| SCHEMBL20195627 | 0.79 | ALDH1A1 (0.48) | SMN1; SMN2ALDH1A1KMT2AATML3MBTL1 | |
| SCHEMBL20195426 | 0.78 | ALDH1A1 (0.50) | SMN1; SMN2ALDH1A1KMT2AATMPOLB | |
| SCHEMBL20195535 | 0.78 | SMN1; SMN2 (0.40) | SMN1; SMN2ALDH1A1KMT2AATML3MBTL1 | |
| SCHEMBL16920895 | 0.74 | MPO (0.44) | SMN1; SMN2ALDH1A1KMT2AGAAPOLB | |
| SCHEMBL17788202 | 0.72 | MPO (0.43) | SMN1; SMN2ALDH1A1KMT2AGAAPOLB | |
| SCHEMBL16920894 | 0.71 | L3MBTL1 (0.48) | SMN1; SMN2ALDH1A1KMT2AL3MBTL1GAA | |
| SCHEMBL6734384 | 0.71 | ALDH1A1 (0.47) | SMN1; SMN2ALDH1A1GAACYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3029035-B1 | TETRAZOLINONE COMPOUND, AND USE THEREOF | SUMITOMO CHEMICAL CO (JP) | 2018-05-30 | — | — | EP | disclosed |