Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA5 | P31644 | 2/20 | 0.43 |
| ▸ | PDK2 | Q15119 | 3/20 | 0.36 |
| ▸ | PDK4 | Q16654 | 2/20 | 0.36 |
| ▸ | RXRA | P19793 | 4/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | SSTR4 | P31391 | 2/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.34 |
| ▸ | SYK | P43405 | 1/20 | 0.34 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.33 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.33 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.33 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20195599 | 0.80 | GABRA5 (0.43) | GABRA5SSTR4SYK | |
| SCHEMBL20195502 | 0.79 | GABRA5 (0.40) | GABRA5PDK2PDK4KDM1ASSTR4 | |
| SCHEMBL20195547 | 0.77 | GABRA5 (0.46) | GABRA5RXRAGRIN1GRIN2BPDE10A | |
| SCHEMBL20195548 | 0.76 | P2RX7 (0.36) | GABRA5PDK2PDK4SSTR4SYK | |
| SCHEMBL18185030 | 0.75 | ADRA1A (0.35) | PDK2PDK4 | |
| SCHEMBL17788186 | 0.75 | HTR6 (0.39) | — | |
| SCHEMBL18504555 | 0.74 | PDE10A (0.32) | PDE10A | |
| SCHEMBL22563834 | 0.74 | PDE10A (0.32) | PDE10A | |
| SCHEMBL18185013 | 0.73 | ADRA1A (0.34) | PDK2PDK4 | |
| SCHEMBL17788201 | 0.73 | MRGPRX4 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3029035-B1 | TETRAZOLINONE COMPOUND, AND USE THEREOF | SUMITOMO CHEMICAL CO (JP) | 2018-05-30 | — | — | EP | disclosed |