Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA5 | P31644 | 1/20 | 0.40 |
| ▸ | HCRTR1 | O43613 | 7/20 | 0.38 |
| ▸ | HCRTR2 | O43614 | 7/20 | 0.38 |
| ▸ | SSTR4 | P31391 | 2/20 | 0.37 |
| ▸ | NR1H4 | Q96RI1 | 4/20 | 0.35 |
| ▸ | SYK | P43405 | 1/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.34 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20195599 | 0.89 | GABRA5 (0.43) | GABRA5HCRTR1HCRTR2SSTR4NR1H4 | |
| SCHEMBL20195491 | 0.84 | SSTR4 (0.40) | GABRA5SSTR4PDK2PDK4 | |
| SCHEMBL20195624 | 0.82 | GABRA5 (0.43) | GABRA5 | |
| SCHEMBL20195626 | 0.80 | GABRA5 (0.42) | GABRA5 | |
| SCHEMBL20195437 | 0.79 | GABRA5 (0.43) | GABRA5SSTR4SYKPDK2PDK4 | |
| SCHEMBL20195640 | 0.79 | TP53 (0.42) | GABRA5HCRTR1HCRTR2 | |
| SCHEMBL18504462 | 0.78 | S1PR1 (0.31) | SSTR4NR1H4 | |
| SCHEMBL20195631 | 0.78 | SSTR4 (0.41) | SSTR4 | |
| SCHEMBL20195498 | 0.78 | SSTR4 (0.41) | SSTR4 | |
| SCHEMBL17788242 | 0.78 | SLC22A12 (0.40) | NR1H4PDK2PDK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3029035-B1 | TETRAZOLINONE COMPOUND, AND USE THEREOF | SUMITOMO CHEMICAL CO (JP) | 2018-05-30 | — | — | EP | disclosed |