Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.36 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 5/20 | 0.36 |
| ▸ | TP53 | P04637 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | NPC1 | O15118 | 4/20 | 0.35 |
| ▸ | RAB9A | P51151 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GBA1 | P04062 | 1/20 | 0.34 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20195661 | 0.82 | RXRA (0.39) | P2RX7GABRA5GRM5GRM1 | |
| SCHEMBL20195662 | 0.82 | P2RX7 (0.40) | P2RX7GRM5TP53MAPTNPC1 | |
| SCHEMBL20195548 | 0.82 | P2RX7 (0.36) | P2RX7GABRA5GRM5GRM1 | |
| SCHEMBL22038669 | 0.79 | HTR7 (0.38) | MAPTNPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL22563891 | 0.79 | NR1H4 (0.37) | MAPTSMN1; SMN2LMNAKDM4EHSD17B10 | |
| SCHEMBL18831735 | 0.77 | GLA (0.39) | MAPTLMNAKMT2AHSD17B10ALDH1A1 | |
| SCHEMBL20195510 | 0.77 | MAPK8 (0.33) | MAPK8GRM5GRM1 | |
| SCHEMBL22037222 | 0.77 | ALDH1A1 (0.40) | TP53MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL22564003 | 0.77 | ALDH1A1 (0.39) | MAPTNPC1RAB9ASMN1; SMN2PKM | |
| SCHEMBL22564358 | 0.76 | NPSR1 (0.34) | TP53MAPTNPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3029035-B1 | TETRAZOLINONE COMPOUND, AND USE THEREOF | SUMITOMO CHEMICAL CO (JP) | 2018-05-30 | — | — | EP | disclosed |