SCHEMBL18831735

SCHEMBL18831735

CCOc1cccc(N(N)C(=O)NN)c1C

nearest known ligand 0.41

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
GLA P06280 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
HCRTR1 O43613 2/20 0.38
GAA P10253 1/20 0.38
KMT2A Q03164 3/20 0.37
EZH2 Q15910 1/20 0.37
LMNA P02545 4/20 0.36
MCL1 Q07820 1/20 0.36
ALDH1A1 P00352 2/20 0.36
HSD17B10 Q99714 1/20 0.36
MEN1 O00255 1/20 0.36
MAPT P10636 1/20 0.36
CYP2C19 P33261 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22563889 0.85 KMT2A (0.41) GLAL3MBTL1HCRTR1GAAKMT2A
SCHEMBL18831312 0.84 CTSD (0.44) L3MBTL1GAAKMT2ALMNAMCL1
SCHEMBL20686658 0.82 L3MBTL1 (0.40) GLAL3MBTL1HCRTR1GAAKMT2A
SCHEMBL20195662 0.78 P2RX7 (0.40) KMT2AALDH1A1HSD17B10MEN1MAPT
SCHEMBL19909862 0.77 ALDH1A1 (0.39) GAAKMT2ALMNAALDH1A1HSD17B10
SCHEMBL20195466 0.77 P2RX7 (0.37) KMT2ALMNAALDH1A1HSD17B10MEN1
SCHEMBL18831350 0.76 ALDH1A1 (0.44) GLAL3MBTL1GAAKMT2ALMNA
SCHEMBL20686606 0.75 HSD17B1 (0.38) L3MBTL1GAAKMT2AALDH1A1MEN1
SCHEMBL19904127 0.75 ALDH1A1 (0.33) GAAKMT2ALMNAALDH1A1HSD17B10
SCHEMBL20195488 0.75 LMNA (0.43) GAAKMT2ALMNAALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2940012-B1 TETRAZOLINONE COMPOUND AND APPLICATIONS THEREOF SUMITOMO CHEMICAL CO (JP) 2019-01-30 EP disclosed
EP-2900655-B1 TETRAZOLINONE COMPOUNDS AND THEIR USE AS PESTICIDES SUMITOMO CHEMICAL CO (JP) 2017-05-10 EP disclosed