Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 3/20 | 0.42 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 4/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.36 |
| ▸ | GBA1 | P04062 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20195626 | 0.89 | GABRA5 (0.42) | GABRA5KDM4EL3MBTL1GRM5NPC1 | |
| SCHEMBL20195590 | 0.89 | GABRA5 (0.44) | TP53GABRA5KDM4EL3MBTL1MAPK8 | |
| SCHEMBL20195624 | 0.84 | GABRA5 (0.43) | GABRA5L3MBTL1NPC1RAB9ALMNA | |
| SCHEMBL20195641 | 0.79 | P2RX7 (0.43) | KDM4EL3MBTL1HCRTR1MAPTMEN1 | |
| SCHEMBL18504683 | 0.79 | KDM4E (0.38) | KDM4EL3MBTL1HCRTR1MAPTRAB9A | |
| SCHEMBL20195502 | 0.79 | GABRA5 (0.40) | GABRA5HCRTR1HCRTR2 | |
| SCHEMBL22564252 | 0.78 | KDM4E (0.37) | KDM4EL3MBTL1HCRTR1MAPTRAB9A | |
| SCHEMBL20195552 | 0.77 | ALDH1A1 (0.43) | L3MBTL1NPC1MAPTRAB9ALMNA | |
| SCHEMBL20195466 | 0.74 | P2RX7 (0.37) | TP53GABRA5KDM4EMAPK8GRM5 | |
| SCHEMBL20195622 | 0.73 | GABRA5 (0.46) | TP53GABRA5NPC1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3029035-B1 | TETRAZOLINONE COMPOUND, AND USE THEREOF | SUMITOMO CHEMICAL CO (JP) | 2018-05-30 | — | — | EP | disclosed |