Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA5 | P31644 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CTSD | P07339 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | VDR | P11473 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | JAK1 | P23458 | 1/20 | 0.35 |
| ▸ | TYK2 | P29597 | 1/20 | 0.35 |
| ▸ | JAK3 | P52333 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20195640 | 0.89 | TP53 (0.42) | GABRA5KMT2AMEN1RXFP1L3MBTL1 | |
| SCHEMBL20195624 | 0.85 | GABRA5 (0.43) | GABRA5KMT2APOLBATML3MBTL1 | |
| SCHEMBL20195668 | 0.84 | RAB9A (0.44) | GABRA5KMT2ACTSDMEN1KDM4E | |
| SCHEMBL20195502 | 0.80 | GABRA5 (0.40) | GABRA5 | |
| SCHEMBL20195587 | 0.79 | P2RX7 (0.43) | KMT2ACTSDMEN1AKR1C3VDR | |
| SCHEMBL20845023 | 0.78 | NPC1 (0.38) | KMT2ACTSDMEN1AKR1C3ATM | |
| SCHEMBL18504485 | 0.78 | CTSD (0.36) | CTSDRXFP1AKR1C3ATML3MBTL1 | |
| SCHEMBL20195547 | 0.78 | GABRA5 (0.46) | GABRA5GRM5ASIC3 | |
| SCHEMBL20195590 | 0.78 | GABRA5 (0.44) | GABRA5KMT2AMEN1L3MBTL1KDM4E | |
| SCHEMBL22564338 | 0.77 | CTSD (0.35) | CTSDRXFP1AKR1C3ATML3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3029035-B1 | TETRAZOLINONE COMPOUND, AND USE THEREOF | SUMITOMO CHEMICAL CO (JP) | 2018-05-30 | — | — | EP | disclosed |