Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA5 | P31644 | 1/20 | 0.40 |
| ▸ | GRM5 | P41594 | 5/20 | 0.38 |
| ▸ | CBFB | Q13951 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20195576 | 0.85 | GABRA5 (0.43) | GABRA5GRM5ALDH1A1NPC1CYP2D6 | |
| SCHEMBL20195549 | 0.80 | ALDH1A1 (0.51) | GABRA5GRM5CBFBALDH1A1NPC1 | |
| SCHEMBL20195588 | 0.79 | HTR1A (0.38) | GABRA5GRM5ALDH1A1NPC1CYP2D6 | |
| SCHEMBL22564151 | 0.78 | PKM (0.32) | ALDH1A1CYP2D6CYP2C19PKM | |
| SCHEMBL18500212 | 0.78 | PKM (0.32) | ALDH1A1CYP2D6CYP2C19KMT2AMEN1 | |
| SCHEMBL20195609 | 0.75 | MEN1 (0.51) | GABRA5ALDH1A1KMT2AMAPK1MEN1 | |
| SCHEMBL20195561 | 0.75 | GABRA5 (0.39) | GABRA5GRM5CBFBALDH1A1NPC1 | |
| SCHEMBL20195550 | 0.74 | ALDH1A1 (0.49) | ALDH1A1NPC1KMT2AMAPK1MEN1 | |
| SCHEMBL20195612 | 0.73 | GRM5 (0.36) | GRM5NPC1CYP2D6CYP2C19KMT2A | |
| SCHEMBL18831616 | 0.72 | ESR1 (0.38) | ALDH1A1KMT2AMEN1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3029035-B1 | TETRAZOLINONE COMPOUND, AND USE THEREOF | SUMITOMO CHEMICAL CO (JP) | 2018-05-30 | — | — | EP | disclosed |