Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 8/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20195639 | 0.85 | BDKRB2 (0.42) | SMN1; SMN2BDKRB2MAPTCYP1A2CYP3A4 | |
| SCHEMBL20195536 | 0.81 | HTR6 (0.35) | HSD17B10LMNABDKRB2TSHRCYP1A2 | |
| SCHEMBL20195589 | 0.81 | ALDH1A1 (0.44) | GRM5KDM4EHSD17B10NPC1LMNA | |
| SCHEMBL20195628 | 0.77 | TP53 (0.44) | KDM4EHSD17B10NPC1LMNARAB9A | |
| SCHEMBL18831616 | 0.77 | ESR1 (0.38) | KDM4EHSD17B10MAPTHTTHPGD | |
| SCHEMBL20195606 | 0.73 | GABRA5 (0.40) | GRM5KDM4ENPC1SMN1; SMN2BDKRB2 | |
| SCHEMBL20195516 | 0.72 | SYK (0.37) | GRM5KDM4ENPC1LMNARAB9A | |
| SCHEMBL17707924 | 0.72 | GRM5 (0.42) | GRM5KDM4EHSD17B10NPC1LMNA | |
| SCHEMBL20195542 | 0.71 | GABRA5 (0.43) | GRM5NPC1RAB9ABDKRB2CYP1A2 | |
| SCHEMBL18831604 | 0.71 | MAPT (0.40) | KDM4ENPC1LMNARAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3029035-B1 | TETRAZOLINONE COMPOUND, AND USE THEREOF | SUMITOMO CHEMICAL CO (JP) | 2018-05-30 | — | — | EP | disclosed |