SCHEMBL20195660

SCHEMBL20195660

CCOc1cccc(N)c1COc1cccnc1C

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.51
DCPS Q96C86 1/20 0.47
GRM5 P41594 3/20 0.40
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
KDM4E B2RXH2 1/20 0.38
POLB P06746 1/20 0.38
MAPT P10636 1/20 0.38
HPGD P15428 1/20 0.38
MAPK1 P28482 1/20 0.38
HSD17B10 Q99714 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
CHRNB2 P17787 2/20 0.38
CHRNA4 P43681 2/20 0.38
LTA4H P09960 1/20 0.38
MAPK14 Q16539 1/20 0.38
MAP4K4 O95819 1/20 0.38
CYP1A2 P05177 1/20 0.37
CYP2C9 P11712 1/20 0.37
CYP2C19 P33261 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20195423 0.84 DCPS (0.52) ALDH1A1DCPSKMT2ACHRNB2CHRNA4
SCHEMBL20195451 0.83 ALDH1A1 (0.45) ALDH1A1GRM5MEN1KMT2AKDM4E
SCHEMBL8325639 0.81 ALDH1A1 (0.52) ALDH1A1DCPSGRM5MEN1KMT2A
SCHEMBL31461865 0.81 ALDH1A1 (0.52) ALDH1A1DCPSGRM5MEN1KMT2A
SCHEMBL20195549 0.80 ALDH1A1 (0.51) ALDH1A1GRM5MEN1KMT2AKDM4E
SCHEMBL20195569 0.78 DCPS (0.43) ALDH1A1DCPSCHRNB2CHRNA4LTA4H
SCHEMBL20195641 0.78 P2RX7 (0.43) ALDH1A1DCPSMEN1KMT2AKDM4E
SCHEMBL16920891 0.76 MRGPRX4 (0.47) ALDH1A1MEN1KMT2AKDM4EPOLB
SCHEMBL18831781 0.75 ALDH1A1 (0.45) ALDH1A1MEN1KMT2AKDM4EPOLB
SCHEMBL16920893 0.74 MAPT (0.59) ALDH1A1MEN1KMT2APOLBMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3029035-B1 TETRAZOLINONE COMPOUND, AND USE THEREOF SUMITOMO CHEMICAL CO (JP) 2018-05-30 EP disclosed