Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 2/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.41 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | IAPP | P10997 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10026827 | 0.87 | ESR1 (0.44) | GABRA1GABRB2ESR1HSPA5TRPA1 | |
| SCHEMBL14099107 | 0.82 | BID (0.45) | GABRA1GABRB2IAPP | |
| SCHEMBL6354470 | 0.81 | IAPP (0.48) | GABRA1GABRB2RIPK1ESR1HSPA5 | |
| SCHEMBL674324 | 0.80 | HSPA5 (0.54) | RIPK1ESR1HSPA5IDO1TSHR | |
| SCHEMBL28092551 | 0.78 | HSPA5 (0.52) | RIPK1ESR1HSPA5IDO1TSHR | |
| SCHEMBL22374130 | 0.78 | ALDH1A1 (0.41) | ATMALDH1A1AKR1B1 | |
| SCHEMBL347746 | 0.78 | GABRA1 (0.61) | GABRA1GABRB2RIPK1ESR1HSPA5 | |
| SCHEMBL15107553 | 0.78 | ANO1 (0.41) | ESR1TRPA1ATMTSHRALDH1A1 | |
| SCHEMBL14682133 | 0.78 | TSHR (0.43) | GABRA1GABRB2ESR1TRPA1ATM | |
| SCHEMBL1839326 | 0.77 | GABRA1 (0.36) | GABRA1GABRB2HSPA5TRPA1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8247589-B2 | Organic silicon phosphate and fabrication method thereof | GRAND TEK ADVANCE MATERIAL SCIENCE CO., LTD. (TW) | 2012-08-21 | — | — | US | claimed |
| US-20110160475-A1 | ORGANIC SILICON PHOSPHATE AND FABRICATION METHOD THEREOF | GRAND TEK ADVANCE MATERIAL SCIENCE CO., LTD. (TW) | 2011-06-30 | — | — | US | claimed |
| CN-102146100-B | Organic silicon phosphate and preparation method thereof | GUANGKE INDUSTRY CO LTD | 2014-07-23 | — | — | CN | disclosed |
| US-8247589-B2 | Organic silicon phosphate and fabrication method thereof | GRAND TEK ADVANCE MATERIAL SCIENCE CO., LTD. (TW) | 2012-08-21 | — | — | US | disclosed |
| CN-102146100-A | Organic silicon phosphate and preparation method thereof | GUANGKE INDUSTRY CO LTD | 2011-08-10 | — | — | CN | disclosed |
| US-20110160475-A1 | ORGANIC SILICON PHOSPHATE AND FABRICATION METHOD THEREOF | GRAND TEK ADVANCE MATERIAL SCIENCE CO., LTD. (TW) | 2011-06-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110160475-A1 | ORGANIC SILICON PHOSPHATE AND FABRICATION METHOD THEREOF | SOST, PTEN, INPP5A | GABRA1 4388/4885GABRB2 4521/4885RIPK1 1070/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.