Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IAPP | P10997 | 4/20 | 0.48 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.48 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | FYN | P06241 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | MMP8 | P22894 | 1/20 | 0.46 |
| ▸ | CA6 | P23280 | 1/20 | 0.46 |
| ▸ | CDK2 | P24941 | 1/20 | 0.46 |
| ▸ | MMP12 | P39900 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL347746 | 0.89 | GABRA1 (0.61) | IAPPGABRA1GABRB2ALDH1A1CA2 | |
| SCHEMBL29356321 | 0.85 | IAPP (0.47) | IAPPGABRA1GABRB2ALDH1A1LMNA | |
| SCHEMBL314108 | 0.83 | GABRA1 (0.54) | GABRA1GABRB2CA2RIPK1ESR1 | |
| SCHEMBL674324 | 0.82 | HSPA5 (0.54) | ALDH1A1HSD17B10CA2TDP1RIPK1 | |
| SCHEMBL24589309 | 0.81 | ALDH1A1 (0.52) | GABRA1GABRB2ALDH1A1HPGDHSD17B10 | |
| SCHEMBL2019599 | 0.81 | GABRA1 (0.41) | IAPPGABRA1GABRB2ALDH1A1TDP1 | |
| SCHEMBL6348843 | 0.80 | ESR1 (0.41) | GABRA1GABRB2RIPK1ESR1 | |
| SCHEMBL28092551 | 0.80 | HSPA5 (0.52) | ALDH1A1HSD17B10CA2TDP1RIPK1 | |
| SCHEMBL70065 | 0.79 | GABRA1 (0.76) | IAPPGABRA1GABRB2ALDH1A1LMNA | |
| SCHEMBL30023472 | 0.79 | GABRA1 (0.76) | IAPPGABRA1GABRB2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10202474-B2 | Process for producing polydienes | BRIDGESTONE CORPORATION (JP) | 2019-02-12 | — | — | US | claimed |
| US-20170073443-A1 | PROCESS FOR PRODUCING POLYDIENES | BRIDGESTONE CORPORATION (US) | 2017-03-16 | — | — | US | claimed |
| US-10822318-B2 | Lactone-based probes and methods of use thereof | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2020-11-03 | — | — | US | disclosed |
| US-10202474-B2 | Process for producing polydienes | BRIDGESTONE CORPORATION (JP) | 2019-02-12 | — | — | US | disclosed |
| US-20170073443-A1 | PROCESS FOR PRODUCING POLYDIENES | BRIDGESTONE CORPORATION (US) | 2017-03-16 | — | — | US | disclosed |
| US-20120022040-A1 | ANTIMICROBIALS | AMPLYX PHARMACEUTICALS, INC. | 2012-01-26 | — | — | US | disclosed |
| US-6878659-B2 | Solid catalyst component for olefin polymerization and catalyst | TOHO TITANIUM CO., LTD. (JP) | 2005-04-12 | — | — | US | disclosed |
| US-20040072681-A1 | Solid catalyst component for olefin polymerization and catalyst | TOHO TITANIUM CO., LTD. (JP) | 2004-04-15 | — | — | US | disclosed |
| EP-1260524-A1 | SOLID CATALYST COMPONENT FOR OLEFIN POLYMERIZATION AND CATALYST | Toho Titanium Co., Ltd. (JP) | 2002-11-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120022040-A1 | ANTIMICROBIALS | PAM, MPO, OXA1L | IAPP 988/4885GABRA1 3593/4885GABRB2 4510/4885 |
| US-10822318-B2 | Lactone-based probes and methods of use thereof | MRPL21, QPCTL, ARGLU1 | IAPP 3981/4885GABRA1 2754/4885GABRB2 3167/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.