Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | JAK1 | P23458 | 1/20 | 0.40 |
| ▸ | TACR1 | P25103 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | STS | P08842 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16838974 | 0.79 | GPR119 (0.45) | GPR119TSHRALOX15ATMUSP30 | |
| SCHEMBL2375967 | 0.74 | PKM (0.56) | GPR119TSHRALOX15ATMUSP30 | |
| SCHEMBL16761886 | 0.73 | TSHR (0.41) | GPR119TSHRALOX15ATMUSP30 | |
| SCHEMBL16838964 | 0.73 | USP30 (0.42) | GPR119USP30ACKR3HDAC1STS | |
| SCHEMBL2375438 | 0.73 | GPR119 (0.50) | GPR119TSHRALOX15ATMUSP30 | |
| SCHEMBL16838949 | 0.72 | ACHE (0.48) | GPR119TSHRALOX15ATMTACR1 | |
| SCHEMBL19960620 | 0.72 | USP2 (0.42) | TSHRALOX15ATMUSP2ALDH1A1 | |
| SCHEMBL3493196 | 0.71 | USP2 (0.39) | TSHRALOX15ATMUSP2ALDH1A1 | |
| SCHEMBL1206023 | 0.70 | TACR1 (0.53) | TSHRALOX15ATMUSP30TACR1 | |
| SCHEMBL11932534 | 0.70 | FAAH (0.57) | ALDH1A1ACKR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2881384-B1 | PARTIALLY SATURATED NITROGEN-CONTAINING HETEROCYCLIC COMPOUND | TAISHO PHARMACEUTICAL CO LTD (JP) | 2018-05-30 | — | — | EP | disclosed |