Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | FDPS | P14324 | 2/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21547665 | 0.85 | HRH3 (0.41) | ALDH1A1CYP1A2TSHRRAB9AHRH3 | |
| SCHEMBL16938329 | 0.84 | ALDH1A1 (0.39) | ALDH1A1CYP1A2TSHRRAB9ANPC1 | |
| SCHEMBL23995490 | 0.83 | HRH1 (0.41) | ALDH1A1CYP1A2TSHRRAB9ANPC1 | |
| SCHEMBL18576871 | 0.79 | TDP1 (0.53) | ALDH1A1CYP1A2TSHRKDM4EMAPT | |
| SCHEMBL22703058 | 0.78 | MAPT (0.55) | ALDH1A1CYP1A2TSHRKDM4EMAPT | |
| SCHEMBL28632625 | 0.78 | ALDH1A1 (0.46) | ALDH1A1CYP1A2TSHRRAB9ANPC1 | |
| SCHEMBL24072727 | 0.76 | TDP1 (0.46) | ALDH1A1CYP1A2TSHRKDM4EMAPT | |
| SCHEMBL21427813 | 0.76 | HTT (0.46) | ALDH1A1CYP1A2TSHRRAB9ANPC1 | |
| SCHEMBL20197335 | 0.75 | RAB9A (0.38) | ALDH1A1CYP1A2TSHRRAB9ANPC1 | |
| SCHEMBL19187746 | 0.75 | CES2 (0.38) | ALDH1A1TSHRSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3209732-B1 | SPHINGOSINE-1-PHOSPATE RECEPTOR MODULATORS FOR TREATMENT OF CARDIOPULMONARY DISORDERS | SCRIPPS RESEARCH INST (US) | 2021-08-04 | — | — | EP | disclosed |