SCHEMBL20198149

SCHEMBL20198149

C=C/C=C(\C=C/C)C(c1ccccc1)N1CCN(C(=O)OC(C(F)(F)F)C(F)(F)F)CC1

nearest known ligand 0.48

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 18/20 0.48
ABHD6 Q9BV23 11/20 0.48
PLA2G7 Q13093 9/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21867746 0.77 MGLL (0.40) MGLLABHD6PLA2G7
SCHEMBL16744460 0.75 MGLL (0.76) MGLLABHD6PLA2G7
SCHEMBL20198108 0.73 MGLL (0.44) MGLLABHD6PLA2G7
SCHEMBL13509298 0.71 MGLL (0.57) MGLLABHD6PLA2G7
SCHEMBL28602160 0.70 MGLL (0.56) MGLLABHD6PLA2G7
SCHEMBL21868486 0.68 ABHD6 (0.45) MGLLABHD6PLA2G7
SCHEMBL21133718 0.68 OPRM1 (0.32)
SCHEMBL16744465 0.67 MGLL (0.79) MGLLABHD6PLA2G7
SCHEMBL16744463 0.67 MGLL (0.56) MGLLABHD6PLA2G7
SCHEMBL23774486 0.66 MGLL (0.51) MGLLABHD6PLA2G7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3326627-A1 CARBAMATE COMPOUNDS AND OF MAKING AND USING SAME Abide Therapeutics, Inc. (US) 2018-05-30 EP disclosed