Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | DRD4 | P21917 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | HRH1 | P35367 | 1/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.45 |
| ▸ | F13A1 | P00488 | 3/20 | 0.43 |
| ▸ | TGM2 | P21980 | 3/20 | 0.43 |
| ▸ | TGM1 | P22735 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 3/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18634193 | 0.95 | F13A1 (0.46) | HTR1ADRD4HTR2AHRH1OPRM1 | |
| SCHEMBL22365059 | 0.84 | MAOA (0.44) | F13A1TGM2TGM1SMN1; SMN2GAA | |
| SCHEMBL20411236 | 0.80 | PKM (0.47) | SMN1; SMN2GAAPKMCNR1L3MBTL1 | |
| SCHEMBL15100844 | 0.78 | MGLL (0.52) | SMN1; SMN2GAAPKMCNR1L3MBTL1 | |
| SCHEMBL16744476 | 0.74 | KMT2A (0.53) | SMN1; SMN2ALDH1A1GAAPKMMEN1 | |
| SCHEMBL20198138 | 0.74 | POLB (0.34) | F13A1TGM2TGM1SMN1; SMN2ALDH1A1 | |
| SCHEMBL18634273 | 0.73 | MGLL (0.53) | SMN1; SMN2ALDH1A1GAAPKMLMNA | |
| SCHEMBL15100865 | 0.70 | MGLL (0.66) | ALDH1A1GAAPKMKMT2AUSP2 | |
| SCHEMBL15232086 | 0.69 | TGM2 (0.62) | F13A1TGM2TGM1SMN1; SMN2GAA | |
| SCHEMBL20408695 | 0.69 | GAA (0.56) | SMN1; SMN2ALDH1A1GAAPKMLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3698782-A1 | CARBAMATE COMPOUNDS FOR USE IN THERAPY | Lundbeck La Jolla Research Center, Inc. (US) | 2020-08-26 | — | — | EP | disclosed |
| EP-3326627-A1 | CARBAMATE COMPOUNDS AND OF MAKING AND USING SAME | Abide Therapeutics, Inc. (US) | 2018-05-30 | — | — | EP | disclosed |