Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | PKM | P14618 | 2/20 | 0.33 |
| ▸ | F13A1 | P00488 | 2/20 | 0.33 |
| ▸ | TGM2 | P21980 | 2/20 | 0.33 |
| ▸ | TGM1 | P22735 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 3/20 | 0.33 |
| ▸ | MGLL | Q99685 | 2/20 | 0.33 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22365059 | 0.80 | MAOA (0.44) | POLBGAASMN1; SMN2PKMF13A1 | |
| SCHEMBL20198164 | 0.74 | HTR1A (0.45) | GAAALDH1A1SMN1; SMN2PKMF13A1 | |
| SCHEMBL18634193 | 0.70 | F13A1 (0.46) | GAAALDH1A1SMN1; SMN2PKMF13A1 | |
| SCHEMBL18634273 | 0.66 | MGLL (0.53) | POLBGAAALDH1A1SMN1; SMN2PKM | |
| SCHEMBL16744476 | 0.65 | KMT2A (0.53) | POLBGAATSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL18634077 | 0.63 | LMNA (0.44) | GAATSHRALDH1A1SMN1; SMN2F13A1 | |
| SCHEMBL20198124 | 0.62 | KMT2A (0.46) | POLBGAAALDH1A1SMN1; SMN2PKM | |
| SCHEMBL18634220 | 0.61 | PKM (0.59) | GAAALDH1A1SMN1; SMN2PKMLMNA | |
| SCHEMBL20408695 | 0.61 | GAA (0.56) | POLBGAAALDH1A1SMN1; SMN2PKM | |
| SCHEMBL15100865 | 0.61 | MGLL (0.66) | GAAALDH1A1PKMMGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3326627-A1 | CARBAMATE COMPOUNDS AND OF MAKING AND USING SAME | Abide Therapeutics, Inc. (US) | 2018-05-30 | — | — | EP | disclosed |