Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 3/20 | 0.61 |
| ▸ | FAAH | O00519 | 1/20 | 0.57 |
| ▸ | MMP13 | P45452 | 1/20 | 0.54 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.51 |
| ▸ | BMP1 | P13497 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 8/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.49 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.49 |
| ▸ | EDNRA | P25101 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | DPP4 | P27487 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3637342 | 0.86 | MMP13 (0.52) | MGLLFAAHMMP13SCD5BMP1 | |
| SCHEMBL27008546 | 0.84 | HPGD (0.67) | MMP13SCD5MAPTNPC1ALDH1A1 | |
| SCHEMBL20408672 | 0.84 | MGLL (0.58) | MGLLFAAHMMP13NPC1ALDH1A1 | |
| SCHEMBL16113168 | 0.83 | OGA (0.60) | SCD5 | |
| SCHEMBL15100627 | 0.82 | MGLL (0.66) | MGLLFAAHHPGD | |
| SCHEMBL15266373 | 0.81 | SCD5 (0.55) | MMP13SCD5BMP1MAPTNPC1 | |
| SCHEMBL18634068 | 0.81 | MGLL (0.55) | MGLLFAAHMMP13NPC1ALDH1A1 | |
| SCHEMBL13074862 | 0.79 | ITGB3 (0.52) | MMP13SCD5BMP1MAPTKEAP1 | |
| SCHEMBL16744482 | 0.78 | MGLL (0.55) | MGLLFAAHMMP13SCD5BMP1 | |
| SCHEMBL14637520 | 0.78 | SMN1; SMN2 (0.53) | MGLLSCD5MAPTALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3326627-A1 | CARBAMATE COMPOUNDS AND OF MAKING AND USING SAME | Abide Therapeutics, Inc. (US) | 2018-05-30 | — | — | EP | disclosed |