Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 3/20 | 0.55 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.52 |
| ▸ | FAAH | O00519 | 2/20 | 0.51 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.49 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 7/20 | 0.48 |
| ▸ | MMP13 | P45452 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | GPR183 | P32249 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | BMP1 | P13497 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15094706 | 0.90 | MGLL (0.69) | MGLLSCD5FAAHKEAP1NFE2L2 | |
| SCHEMBL15100631 | 0.88 | MGLL (0.53) | MGLLSCD5FAAHKEAP1NFE2L2 | |
| SCHEMBL16744471 | 0.84 | MGLL (0.79) | MGLLFAAH | |
| SCHEMBL20408673 | 0.83 | MGLL (0.66) | MGLLSCD5FAAHMMP13POLB | |
| SCHEMBL31023747 | 0.81 | SCD5 (0.51) | MGLLSCD5KEAP1NFE2L2MAPT | |
| SCHEMBL31023722 | 0.80 | MGLL (0.49) | MGLLSCD5KEAP1NFE2L2MAPT | |
| SCHEMBL14637520 | 0.79 | SMN1; SMN2 (0.53) | MGLLSCD5KEAP1NFE2L2MAPT | |
| SCHEMBL22365061 | 0.79 | MGLL (0.53) | MGLLSCD5FAAHKEAP1NFE2L2 | |
| SCHEMBL16114136 | 0.78 | BMP1 (0.53) | SCD5KEAP1NFE2L2MAPTMMP13 | |
| SCHEMBL20198176 | 0.78 | MGLL (0.61) | MGLLSCD5FAAHKEAP1NFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230312499-A1 | CARBAMATE COMPOUNDS AND METHODS OF MAKING AND USING SAME | H. LUNDBECK A/S (DK) | 2023-10-05 | — | — | US | disclosed |
| US-20180208568-A1 | CARBAMATE COMPOUNDS AND METHODS OF MAKING AND USING SAME | H. LUNDBECK A/S (DK) | 2018-07-26 | — | — | US | disclosed |
| US-9957242-B2 | Carbamate compounds and methods of making and using same | THE SCRIPPS RESEARCH INSTITUTE (US) | 2018-05-01 | — | — | US | disclosed |
| US-20170073320-A1 | CARBAMATE COMPOUNDS AND METHODS OF MAKING AND USING SAME | H. LUNDBECK A/S (DK) | 2017-03-16 | — | — | US | disclosed |
| US-9487495-B2 | Carbamate compounds and of making and using same | THE SCRIPTS RESEARCH INSTITUTE (US) | 2016-11-08 | — | — | US | disclosed |
| US-9133148-B2 | Carbamate compounds and of making and using same | THE SCRIPPS RESEARCH INSTITUTE (US) | 2015-09-15 | — | — | US | disclosed |
| US-20150148330-A1 | CARBAMATE COMPOUNDS AND OF MAKING AND USING SAME | H. LUNDBECK A/S (DK) | 2015-05-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180208568-A1 | CARBAMATE COMPOUNDS AND METHODS OF MAKING AND USING SAME | ABHD6, ABHD16A, NCEH1 | MGLL 14/4885SCD5 680/4885FAAH 4/4885 |
| US-20230312499-A1 | CARBAMATE COMPOUNDS AND METHODS OF MAKING AND USING SAME | ABHD6, ABHD16A, RABL6 | MGLL 54/4885SCD5 1767/4885FAAH 5/4885 |
| US-20150148330-A1 | CARBAMATE COMPOUNDS AND OF MAKING AND USING SAME | ABHD6, ABHD16A, PRMT6 | MGLL 16/4885SCD5 640/4885FAAH 10/4885 |
| US-20170073320-A1 | CARBAMATE COMPOUNDS AND METHODS OF MAKING AND USING SAME | ABHD6, ABHD16A, NCEH1 | MGLL 14/4885SCD5 680/4885FAAH 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.