Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 7/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.46 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.46 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.46 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.46 |
| ▸ | MMP1 | P03956 | 3/20 | 0.44 |
| ▸ | MMP2 | P08253 | 3/20 | 0.44 |
| ▸ | MMP9 | P14780 | 3/20 | 0.44 |
| ▸ | MMP8 | P22894 | 3/20 | 0.44 |
| ▸ | MMP12 | P39900 | 3/20 | 0.44 |
| ▸ | MMP13 | P45452 | 3/20 | 0.44 |
| ▸ | MMP14 | P50281 | 3/20 | 0.44 |
| ▸ | MMP16 | P51512 | 3/20 | 0.44 |
| ▸ | MMP3 | P08254 | 2/20 | 0.43 |
| ▸ | SFRP1 | Q8N474 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20198343 | 0.86 | HSD11B1 (0.54) | HTR6SMN1; SMN2ALDH1A1POLBMAPT | |
| SCHEMBL4135815 | 0.85 | HTR6 (0.51) | HTR6SMN1; SMN2ALDH1A1POLBMAPT | |
| SCHEMBL30513963 | 0.80 | ALDH1A1 (0.54) | HTR6SMN1; SMN2ALDH1A1POLBMAPT | |
| SCHEMBL2487383 | 0.80 | ALDH1A1 (0.54) | HTR6SMN1; SMN2ALDH1A1POLBMAPT | |
| SCHEMBL28053976 | 0.80 | MMP1 (0.55) | HTR6POLBABCC9ABCC8KCNJ11 | |
| SCHEMBL4402282 | 0.80 | ALDH1A1 (0.53) | HTR6SMN1; SMN2ALDH1A1POLBMAPT | |
| SCHEMBL4403011 | 0.80 | ALDH1A1 (0.49) | HTR6SMN1; SMN2ALDH1A1POLBMAPT | |
| SCHEMBL12336792 | 0.80 | HTR6 (0.58) | HTR6SMN1; SMN2ALDH1A1POLBMAPT | |
| SCHEMBL4400959 | 0.79 | HTR6 (0.56) | HTR6SMN1; SMN2ALDH1A1POLBMAPT | |
| SCHEMBL197508 | 0.79 | HTR6 (0.78) | HTR6SMN1; SMN2ALDH1A1POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1675930-B1 | NEW MATERIALS FOR ELECTROLUMINESCENCE AND THE UTILIZATION THEREOF | MERCK PATENT GMBH (DE) | 2018-05-30 | — | — | EP | disclosed |