Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.54 |
| ▸ | HTR6 | P50406 | 6/20 | 0.52 |
| ▸ | MMP1 | P03956 | 6/20 | 0.50 |
| ▸ | MMP2 | P08253 | 6/20 | 0.50 |
| ▸ | MMP9 | P14780 | 6/20 | 0.50 |
| ▸ | MMP12 | P39900 | 6/20 | 0.50 |
| ▸ | MMP13 | P45452 | 6/20 | 0.50 |
| ▸ | MMP14 | P50281 | 6/20 | 0.50 |
| ▸ | MMP8 | P22894 | 5/20 | 0.50 |
| ▸ | MMP16 | P51512 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | MMP3 | P08254 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.47 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.47 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.47 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28053976 | 0.94 | MMP1 (0.55) | HSD11B1HTR6MMP1MMP2MMP9 | |
| SCHEMBL12336792 | 0.94 | HTR6 (0.58) | HSD11B1HTR6ALDH1A1SMN1; SMN2POLB | |
| (Phenylsulfonyl)Benzene SCHEMBL6332793 | 0.92 | HTR6 (0.61) | HSD11B1HTR6ALDH1A1SMN1; SMN2POLB | |
| SCHEMBL1713160 | 0.90 | HTR6 (0.57) | HSD11B1HTR6ALDH1A1SMN1; SMN2POLB | |
| SCHEMBL31092469 | 0.90 | HTR6 (0.57) | HSD11B1HTR6ALDH1A1SMN1; SMN2POLB | |
| (Phenylsulfonyl)Benzene SCHEMBL10595193 | 0.88 | HTR6 (0.61) | HSD11B1HTR6ALDH1A1SMN1; SMN2POLB | |
| SCHEMBL20198254 | 0.86 | HTR6 (0.58) | HSD11B1HTR6MMP1MMP2MMP9 | |
| SCHEMBL27713196 | 0.85 | HSD11B1 (0.53) | HSD11B1HTR6ALDH1A1SMN1; SMN2POLB | |
| SCHEMBL4402282 | 0.83 | ALDH1A1 (0.53) | HTR6MMP1MMP2MMP9MMP12 | |
| SCHEMBL30893040 | 0.82 | GAA (0.60) | HSD11B1ALDH1A1SMN1; SMN2MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1675930-B1 | NEW MATERIALS FOR ELECTROLUMINESCENCE AND THE UTILIZATION THEREOF | MERCK PATENT GMBH (DE) | 2018-05-30 | — | — | EP | disclosed |