Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19965631 | 0.80 | NR1I2 (0.31) | — | |
| SCHEMBL19853062 | 0.79 | DNM1 (0.34) | — | |
| SCHEMBL22810433 | 0.78 | — | — | |
| SCHEMBL23869504 | 0.77 | NR1I2 (0.34) | — | |
| SCHEMBL21346764 | 0.77 | NR1I2 (0.34) | — | |
| SCHEMBL20376381 | 0.67 | APLNR (0.38) | — | |
| SCHEMBL19232123 | 0.66 | GPR84 (0.37) | — | |
| SCHEMBL19853068 | 0.66 | APLNR (0.40) | — | |
| SCHEMBL20200390 | 0.66 | — | — | |
| SCHEMBL12193894 | 0.65 | BDKRB2 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018097944-A1 | TRIAZOLE FURAN COMPOUNDS AS AGONISTS OF THE APJ RECEPTOR | AMGEN INC. (US) | 2018-05-31 | — | — | WO | disclosed |