Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.77 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.77 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.77 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.77 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.77 |
| ▸ | MAPT | P10636 | 3/20 | 0.77 |
| ▸ | FBP1 | P09467 | 2/20 | 0.77 |
| ▸ | SLCO2B1 | O94956 | 2/20 | 0.77 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.77 |
| ▸ | HPGD | P15428 | 2/20 | 0.77 |
| ▸ | APEX1 | P27695 | 2/20 | 0.77 |
| ▸ | DAPK1 | P53355 | 2/20 | 0.77 |
| ▸ | GLA | P06280 | 1/20 | 0.77 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.77 |
| ▸ | RAD52 | P43351 | 1/20 | 0.77 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.77 |
| ▸ | TST | Q16762 | 1/20 | 0.77 |
| ▸ | BCL9 | O00512 | 7/20 | 0.62 |
| ▸ | CTNNB1 | P35222 | 7/20 | 0.62 |
| ▸ | CDK1 | P06493 | 3/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Gossypetin SCHEMBL29419067 | 0.87 | MEN1 (1.00) | MEN1KMT2AKDM4ECYP19A1ALOX15 | |
| Gossypetin SCHEMBL157033 | 0.87 | MEN1 (1.00) | MEN1KMT2AKDM4ECYP19A1ALOX15 | |
| Gossypetin SCHEMBL29929428 | 0.87 | MEN1 (1.00) | MEN1KMT2AKDM4ECYP19A1ALOX15 | |
| SCHEMBL16682485 | 0.86 | FBP1 (0.78) | MEN1KMT2AKDM4ECYP19A1ALOX15 | |
| Gossypetin SCHEMBL16782915 | 0.86 | MEN1 (0.97) | MEN1KMT2AKDM4ECYP19A1ALOX15 | |
| SCHEMBL12640014 | 0.84 | MEN1 (0.77) | MEN1KMT2AKDM4ECYP19A1ALOX15 | |
| SCHEMBL30190288 | 0.84 | MEN1 (0.77) | MEN1KMT2AKDM4ECYP19A1ALOX15 | |
| Herbacetin SCHEMBL31442430 | 0.82 | FBP1 (1.00) | MEN1KMT2AKDM4ECYP19A1ALOX15 | |
| Herbacetin SCHEMBL872691 | 0.82 | FBP1 (1.00) | MEN1KMT2AKDM4ECYP19A1ALOX15 | |
| SCHEMBL13857095 | 0.81 | MEN1 (0.77) | MEN1KMT2AKDM4ECYP19A1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180209956-A1 | HTS Assay for Identifying Small Molecule Inhibitors of RAD52 and Uses of Identified Small Molecule Inhibitors for Treatment and Prevention of BRCA-Deficient Malignancies | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 2018-07-26 | — | — | US | disclosed |
| US-20180147223-A1 | BOTULINUM NEUROTOXIN INHIBITORS | Prime Bio, Inc (US) | 2018-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180147223-A1 | BOTULINUM NEUROTOXIN INHIBITORS | BTD, ACHE, GABBR1 | MEN1 1735/4885KMT2A 3872/4885KDM4E 2847/4885 |
| US-20180209956-A1 | HTS Assay for Identifying Small Molecule Inhibitors of RAD52 and Uses of Identified Small Molecule Inhibitors for Treatment and Prevention of BRCA-Deficient Malignancies | RAD52, BRCA1, RAD50 | MEN1 1087/4885KMT2A 924/4885KDM4E 3907/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.