SCHEMBL20201280

SCHEMBL20201280

c1ccc(-c2cccc3c2sc2cc(N(c4ccccc4)c4ccc5c(c4)sc4ccc(N(c6ccccc6)c6ccc7sc8ccccc8c7c6)cc45)ccc23)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.46
F9 P00740 1/20 0.38
LIMK1 P53667 4/20 0.36
MAPT P10636 3/20 0.36
ALDH1A1 P00352 2/20 0.36
HPGD P15428 1/20 0.36
RAB9A P51151 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
PRKDC P78527 3/20 0.36
PARP14 Q460N5 1/20 0.36
TNKS O95271 1/20 0.35
TNKS2 Q9H2K2 1/20 0.35
GPR3 P46089 1/20 0.34
POLB P06746 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
SLC9A1 P19634 1/20 0.32
PTGIR P43119 1/20 0.32
CYP1A2 P05177 1/20 0.32
PIK3CD O00329 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21281867 0.98 ALOX5 (0.47) ALOX5F9LIMK1MAPTALDH1A1
SCHEMBL21281916 0.98 ALOX5 (0.49) ALOX5F9LIMK1MAPTALDH1A1
SCHEMBL15964385 0.94 ALOX5 (0.52) ALOX5F9LIMK1MAPTALDH1A1
SCHEMBL15614312 0.93 ALOX5 (0.44) ALOX5F9LIMK1MAPTALDH1A1
SCHEMBL15614186 0.93 ALOX5 (0.52) ALOX5F9LIMK1MAPTALDH1A1
SCHEMBL15614322 0.93 ALOX5 (0.49) ALOX5F9LIMK1MAPTALDH1A1
SCHEMBL12283342 0.93 ALOX5 (0.51) ALOX5F9LIMK1MAPTALDH1A1
SCHEMBL15964380 0.93 ALOX5 (0.51) ALOX5F9LIMK1MAPTALDH1A1
SCHEMBL12283343 0.93 ALOX5 (0.51) ALOX5F9LIMK1MAPTALDH1A1
SCHEMBL15964384 0.93 ALOX5 (0.51) ALOX5F9LIMK1MAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210098706-A1 ORGANIC ELECTRIC ELEMENT COMPRISING COMPOUND FOR ORGANIC ELECTRIC ELEMENT AND ELECTRONIC DEVICE THEREOF DUK SAN NEOLUX CO., LTD. (KR) 2021-04-01 US disclosed
US-10319915-B2 Compound for organic electronic element, organic electronic element using the same, and an electronic device thereof DUK SAN NEOLUX CO., LTD. (KR) 2019-06-11 US disclosed
US-20180151806-A2 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING THE SAME, AND AN ELECTRONIC DEVICE THEREOF DUK SAN NEOLUX CO., LTD. (KR) 2018-05-31 US disclosed
US-20180151806-A2 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING THE SAME, AND AN ELECTRONIC DEVICE THEREOF DUK SAN NEOLUX CO., LTD. (KR) 2018-05-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210098706-A1 ORGANIC ELECTRIC ELEMENT COMPRISING COMPOUND FOR ORGANIC ELECTRIC ELEMENT AND ELECTRONIC DEVICE THEREOF EED, PIEZO1, TRPA1 ALOX5 1889/4885F9 1379/4885LIMK1 163/4885
US-10319915-B2 Compound for organic electronic element, organic electronic element using the same, and an electronic device thereof EML4, EBPL, NFE2L2 ALOX5 1123/4885F9 1945/4885LIMK1 916/4885
US-20180151806-A2 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING THE SAME, AND AN ELECTRONIC DEVICE THEREOF EBPL, EML4, NFE2L2 ALOX5 791/4885F9 2016/4885LIMK1 903/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.