Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP4 | P15090 | 3/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | CHUK | O15111 | 1/20 | 0.32 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.32 |
| ▸ | FEN1 | P39748 | 1/20 | 0.32 |
| ▸ | ACACB | O00763 | 1/20 | 0.32 |
| ▸ | HRH2 | P25021 | 1/20 | 0.30 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20204868 | 0.92 | ADRA1A (0.40) | FABP4ADRA1AHTR2CPDE4DCHUK | |
| SCHEMBL20207781 | 0.92 | ADRA1A (0.40) | FABP4ADRA1AHTR2CPDE4DCHUK | |
| SCHEMBL20206761 | 0.83 | FEN1 (0.36) | HCRTR1HCRTR2HTR2CALOX5APFEN1 | |
| SCHEMBL20376466 | 0.83 | FEN1 (0.36) | HCRTR1HCRTR2HTR2CALOX5APFEN1 | |
| SCHEMBL21324930 | 0.83 | FABP4 (0.35) | FABP4ADRA1AHCRTR1HCRTR2ALOX5AP | |
| SCHEMBL21324914 | 0.83 | FABP4 (0.37) | FABP4ADRA1AHCRTR1HCRTR2HTR2C | |
| SCHEMBL21533824 | 0.83 | FABP4 (0.37) | FABP4ADRA1AHCRTR1HCRTR2HTR2C | |
| SCHEMBL22751137 | 0.79 | FABP4 (0.39) | FABP4ADRA1AHCRTR1HCRTR2HTR2C | |
| SCHEMBL20206774 | 0.77 | ADRA1A (0.38) | FABP4ADRA1AHTR2CPDE4DCHUK | |
| SCHEMBL21324913 | 0.77 | ADRA1A (0.38) | FABP4ADRA1AHTR2CPDE4DCHUK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018098207-A1 | HYDANTOIN CONTAINING DEOXYURIDINE TRIPHOSPHATASE INHIBITORS | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2018-05-31 | — | — | WO | disclosed |
| WO-2018098209-A1 | AMINO SULFONYL COMPOUNDS | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2018-05-31 | — | — | WO | disclosed |
| WO-2018098206-A1 | HYDANTOIN CONTAINING DEOXYURIDINE TRIPHOSPHATASE INHIBITORS | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2018-05-31 | — | — | WO | disclosed |