SCHEMBL20202082

SCHEMBL20202082

COCCOC(=O)c1ccc(C(C)=O)cn1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 2/20 0.53
L3MBTL1 Q9Y468 2/20 0.46
KDM4E B2RXH2 1/20 0.46
TSHR P16473 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.43
RXFP1 Q9HBX9 1/20 0.43
MEN1 O00255 1/20 0.42
AHR P35869 1/20 0.42
KMT2A Q03164 1/20 0.42
HCAR3 P49019 1/20 0.40
P4HTM Q9NXG6 4/20 0.39
ABCB11 O95342 1/20 0.39
CYP3A4 P08684 1/20 0.39
ADRA2B P18089 1/20 0.39
OPRD1 P41143 1/20 0.39
SCN5A Q14524 1/20 0.39
GAA P10253 1/20 0.39
P4HA1 P13674 1/20 0.39
MIF P14174 1/20 0.39
PKM P14618 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9342407 0.91 MAPK1 (0.60) MAPK1L3MBTL1KDM4ETSHRSMN1; SMN2
SCHEMBL20202080 0.84 MAPK1 (0.43) MAPK1L3MBTL1KDM4ESMN1; SMN2RXFP1
SCHEMBL16998556 0.83 MAPK1 (0.53) MAPK1L3MBTL1KDM4ESMN1; SMN2RXFP1
SCHEMBL989398 0.80 MAPK1 (0.79) MAPK1L3MBTL1KDM4EMEN1AHR
SCHEMBL7356957 0.80 MAPK1 (0.51) MAPK1L3MBTL1KDM4ETSHRHCAR3
SCHEMBL14001767 0.79 TSHR (0.56) MAPK1L3MBTL1TSHRSMN1; SMN2KMT2A
SCHEMBL9918169 0.79 TSHR (0.56) MAPK1L3MBTL1TSHRSMN1; SMN2KMT2A
SCHEMBL20202083 0.78 TSHR (0.45) KDM4ETSHRSMN1; SMN2RXFP1KMT2A
SCHEMBL14480266 0.76 MAPT (0.50) L3MBTL1HCAR3GAA
SCHEMBL338813 0.76 ALDH1A1 (0.57) MAPK1L3MBTL1KDM4ETSHRSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11807886-B2 Process for the preparation of copolymers derived from 2,4- or 2,5-pyridinedicarboxylic acid BIOME BIOPLASTICS LIMITED (GB) 2023-11-07 US disclosed
US-11807886-B2 Process for the preparation of copolymers derived from 2,4- or 2,5-pyridinedicarboxylic acid BIOME BIOPLASTICS LIMITED (GB) 2023-11-07 US disclosed
US-20180148752-A1 PROCESS FOR THE PREPARATION OF 2,4- OR 2,5-PYRIDINEDICARBOXYLIC ACID AND COPOLYMERS DERIVED THEREFROM BIOME BIOPLASTICS LIMITED (GB) 2018-05-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11807886-B2 Process for the preparation of copolymers derived from 2,4- or 2,5-pyridinedicarboxylic acid HPD, PGD, PCCA MAPK1 3440/4885L3MBTL1 4557/4885KDM4E 378/4885
US-20180148752-A1 PROCESS FOR THE PREPARATION OF 2,4- OR 2,5-PYRIDINEDICARBOXYLIC ACID AND COPOLYMERS DERIVED THEREFROM HPD, PCCA, MVD MAPK1 2904/4885L3MBTL1 4344/4885KDM4E 657/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.