SCHEMBL20202083

SCHEMBL20202083

COCCOC(=O)c1cc(C(C)=O)ccn1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.45
KDM4E B2RXH2 2/20 0.40
KDM6B O15054 2/20 0.40
KDM5C P41229 2/20 0.40
KDM4C Q9H3R0 2/20 0.40
KDM2A Q9Y2K7 2/20 0.40
KDM3A Q9Y4C1 2/20 0.40
ALDH1A1 P00352 2/20 0.40
MAPT P10636 2/20 0.40
KDM5B Q9UGL1 2/20 0.40
TET3 O43151 1/20 0.40
KDM4A O75164 1/20 0.40
BBOX1 O75936 1/20 0.40
KDM5A P29375 1/20 0.40
ASPH Q12797 1/20 0.40
KDM4D Q6B0I6 1/20 0.40
TET2 Q6N021 1/20 0.40
ALKBH5 Q6P6C2 1/20 0.40
KDM7A Q6ZMT4 1/20 0.40
KDM8 Q8N371 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9561789 0.91 TSHR (0.47) TSHRKDM4EKDM6BKDM5CKDM4C
SCHEMBL20202081 0.85 KMT2A (0.42) KDM4EKDM6BKDM5CKDM4CKDM2A
SCHEMBL9297593 0.83 CYP1A2 (0.49) KDM4EKDM6BKDM5CKDM4CKDM2A
SCHEMBL30236802 0.81 KDM4E (0.50) KDM4EKDM6BKDM5CKDM4CKDM2A
SCHEMBL4939178 0.81 KDM4E (0.50) KDM4EKDM6BKDM5CKDM4CKDM2A
SCHEMBL726595 0.81 RECQL (0.47) TSHRALDH1A1MAPTRXFP1GRM4
SCHEMBL20202082 0.78 MAPK1 (0.53) TSHRKDM4ESMN1; SMN2RXFP1KMT2A
SCHEMBL8406007 0.77 JMJD6 (0.59) TSHRKDM4EKDM6BKDM5CKDM4C
SCHEMBL9345772 0.77 SMN1; SMN2 (0.50) TSHRKDM4EKDM6BKDM5CKDM4C
SCHEMBL9927399 0.75 TSHR (0.54) TSHRKDM4EALDH1A1MAPTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11807886-B2 Process for the preparation of copolymers derived from 2,4- or 2,5-pyridinedicarboxylic acid BIOME BIOPLASTICS LIMITED (GB) 2023-11-07 US disclosed
US-20180148752-A1 PROCESS FOR THE PREPARATION OF 2,4- OR 2,5-PYRIDINEDICARBOXYLIC ACID AND COPOLYMERS DERIVED THEREFROM BIOME BIOPLASTICS LIMITED (GB) 2018-05-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11807886-B2 Process for the preparation of copolymers derived from 2,4- or 2,5-pyridinedicarboxylic acid HPD, PGD, PCCA TSHR 4853/4885KDM4E 378/4885KDM6B 647/4885
US-20180148752-A1 PROCESS FOR THE PREPARATION OF 2,4- OR 2,5-PYRIDINEDICARBOXYLIC ACID AND COPOLYMERS DERIVED THEREFROM HPD, PCCA, MVD TSHR 4864/4885KDM4E 657/4885KDM6B 484/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.