SCHEMBL20185747

SCHEMBL20185747

CN(C(=O)OC(C)(C)C)C(CSC(c1ccccc1)(c1ccccc1)c1ccccc1)C(=O)O

nearest known ligand 0.49

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 19/20 0.49
DNMT1 P26358 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8370224 1.00 KIF11 (0.49) KIF11DNMT1
SCHEMBL21084958 1.00 KIF11 (0.49) KIF11DNMT1
SCHEMBL20202843 0.91 KIF11 (0.48) KIF11DNMT1
SCHEMBL20202835 0.88 MMP13 (0.44) KIF11DNMT1
SCHEMBL2818358 0.88 KIF11 (0.43) KIF11DNMT1
SCHEMBL2818361 0.88 KIF11 (0.43) KIF11DNMT1
SCHEMBL8416048 0.87 KIF11 (0.42) KIF11DNMT1
SCHEMBL24360323 0.85 KIF11 (0.47) KIF11DNMT1
SCHEMBL24360324 0.85 KIF11 (0.47) KIF11DNMT1
SCHEMBL24360331 0.84 KIF11 (0.46) KIF11DNMT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260015313-A1 AMINO ACID ACTIVE ESTER AND SALT THEREOF PEPTIDREAM INC (JP) 2026-01-15 US disclosed
EP-4534524-A1 AMINO ACID ACTIVE ESTER AND SALT THEREOF PeptiDream Inc. (JP) 2025-04-09 EP disclosed
CN-118178369-A Application of aminothiol compound as cerebral nerve or heart protecting agent 上海科州药物研发有限公司 2024-06-14 CN disclosed
CN-114072381-B Application of aminothiol compound as cerebral nerve or heart protecting agent 上海科州药物研发有限公司 2024-02-27 CN disclosed
EP-3508476-B1 AMINO MERCAPTAN COMPOUND AND PREPARATION METHOD THEREFOR AND USE THEREOF IN PROTECTION AGAINST RADIATION SHANGHAI KECHOW PHARMA INC (CN) 2023-11-22 EP disclosed
US-20220259164-A1 USE OF AMINOTHIOL COMPOUNDS AS CEREBRAL NERVE OR HEART PROTECTIVE AGENT SHANGHAI KECHOW PHARMA, INC. (CN) 2022-08-18 US disclosed
EP-3984993-A1 USE OF AMINOTHIOL COMPOUNDS AS CEREBRAL NERVE OR HEART PROTECTIVE AGENT Shanghai Kechow Pharma, Inc. (CN) 2022-04-20 EP disclosed
CN-112480122-B Tetrahydroimidazo [1,2-a ] pyrazine compound, composition, preparation method and application thereof 中山大学 2022-03-22 CN disclosed
CN-114072381-A Use of aminothiol compounds as neurocerebroprotective or cardioprotective agents 上海科州药物研发有限公司 2022-02-18 CN disclosed
CN-110167915-B Amino-thiol compound, preparation method thereof and application thereof in radiation protection 上海科州药物研发有限公司 2021-11-26 CN disclosed
US-11008286-B2 Amino mercaptan compound and preparation method therefor and use thereof in protection against radiation SHANGHAI KECHOW PHARMA, INC (CN) 2021-05-18 US disclosed
CN-112480122-A Tetrahydroimidazo [1,2-a ] pyrazine compound, composition, preparation method and application thereof 中山大学 2021-03-12 CN disclosed
WO-2020249120-A1 USE OF AMINOTHIOL COMPOUNDS AS CEREBRAL NERVE OR HEART PROTECTIVE AGENT 上海科州药物研发有限公司 2020-12-17 WO disclosed
US-10413583-B2 Synthetic substrates for enzymes that catalyze reactions of modified cysteines and related methods THE UNIVERSITY OF CHICAGO (US) 2019-09-17 US disclosed
EP-3508476-A1 AMINO MERCAPTAN COMPOUND AND PREPARATION METHOD THEREFOR AND USE THEREOF IN PROTECTION AGAINST RADIATION Inst Of Radiation Medicine Chinese Acad Of Medical Sciences (CN) 2019-07-10 EP disclosed
US-20190202779-A1 AMINO MERCAPTAN COMPOUND AND PREPARATION METHOD THEREFOR AND USE THEREOF IN PROTECTION AGAINST RADIATION SHANGHAI KECHOW PHARMA, INC. (CN) 2019-07-04 US disclosed
US-20180147250-A1 SYNTHETIC SUBSTRATES FOR ENZYMES THAT CATALYZE REACTIONS OF MODIFIED CYSTEINES AND RELATED METHODS THE UNIVERSITY OF CHICAGO 2018-05-31 US disclosed
US-20180147250-A1 SYNTHETIC SUBSTRATES FOR ENZYMES THAT CATALYZE REACTIONS OF MODIFIED CYSTEINES AND RELATED METHODS THE UNIVERSITY OF CHICAGO 2018-05-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190202779-A1 AMINO MERCAPTAN COMPOUND AND PREPARATION METHOD THEREFOR AND USE THEREOF IN PROTECTION AGAINST RADIATION MGMT, PRMT8, SULT1A1 KIF11 4017/4885DNMT1 1552/4885
US-20260015313-A1 AMINO ACID ACTIVE ESTER AND SALT THEREOF NSUN3, BCAT1, SLC43A1 KIF11 3394/4885DNMT1 1890/4885
US-11008286-B2 Amino mercaptan compound and preparation method therefor and use thereof in protection against radiation MGMT, GSTA1, PRMT1 KIF11 3193/4885DNMT1 1065/4885
US-10413583-B2 Synthetic substrates for enzymes that catalyze reactions of modified cysteines and related methods DNPEP, PTMS, CTH KIF11 4826/4885DNMT1 2205/4885
US-20180147250-A1 SYNTHETIC SUBSTRATES FOR ENZYMES THAT CATALYZE REACTIONS OF MODIFIED CYSTEINES AND RELATED METHODS DNPEP, PTMS, CTH KIF11 4826/4885DNMT1 2205/4885
US-20220259164-A1 USE OF AMINOTHIOL COMPOUNDS AS CEREBRAL NERVE OR HEART PROTECTIVE AGENT TNNI3, TNNT2, AADAT KIF11 4607/4885DNMT1 3803/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.