Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 10/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23718330 | 0.79 | TRPA1 (0.41) | TRPA1 | |
| SCHEMBL25165827 | 0.75 | TRPA1 (0.36) | TRPA1 | |
| SCHEMBL22210503 | 0.73 | ADORA2A (0.39) | TRPA1 | |
| SCHEMBL21363473 | 0.73 | TRPA1 (0.41) | TRPA1 | |
| SCHEMBL21363539 | 0.70 | ADORA2B (0.41) | TRPA1 | |
| SCHEMBL17164066 | 0.63 | ALDH1A1 (0.45) | — | |
| SCHEMBL20203174 | 0.60 | ADORA2A (0.48) | TRPA1 | |
| SCHEMBL21363714 | 0.59 | TRPA1 (0.35) | TRPA1 | |
| SCHEMBL24754257 | 0.59 | KDM4E (0.50) | — | |
| SCHEMBL10006798 | 0.58 | NOS1 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018096159-A1 | OXADIAZOLONES AS TRANSIENT RECEPTOR POTENTIAL CHANNEL INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2018-05-31 | — | — | WO | disclosed |