Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CASP3 | P42574 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.31 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.31 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19195022 | 0.79 | HMBS (0.37) | MAPK1SMN1; SMN2NPC1LMNACASP3 | |
| SCHEMBL20374478 | 0.75 | HPGD (0.31) | MAPK1ATMNPSR1 | |
| SCHEMBL12119416 | 0.68 | ADRB2 (0.52) | SMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL22038840 | 0.68 | ATAD2 (0.45) | SMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL14163824 | 0.68 | LMNA (0.32) | MAPK1SMN1; SMN2NPC1LMNACASP3 | |
| SCHEMBL18800357 | 0.68 | DAO (0.41) | MAPK1SMN1; SMN2NPC1LMNACASP3 | |
| SCHEMBL12943015 | 0.67 | GABRA1 (0.46) | MAPK1SMN1; SMN2ATMMEN1ALDH1A1 | |
| SCHEMBL13462923 | 0.67 | PDE3B (0.33) | MAPK1SMN1; SMN2NPC1LMNACASP3 | |
| SCHEMBL26265738 | 0.67 | ERCC1 (0.36) | MAPK1SMN1; SMN2NPC1LMNACASP3 | |
| SCHEMBL28901167 | 0.65 | WEE1 (0.36) | MAPK1SMN1; SMN2NPC1LMNACASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018098209-A1 | AMINO SULFONYL COMPOUNDS | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2018-05-31 | — | — | WO | disclosed |