Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 5/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.37 |
| ▸ | NOS3 | P29474 | 1/20 | 0.37 |
| ▸ | NOS1 | P29475 | 1/20 | 0.37 |
| ▸ | NOS2 | P35228 | 1/20 | 0.37 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | SNRNP200 | O75643 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20204891 | 0.79 | BCHE (0.43) | BCHESNRNP200 | |
| SCHEMBL21536684 | 0.70 | DUT (0.43) | MEN1KMT2AALDH1A1SNRNP200 | |
| SCHEMBL20204819 | 0.66 | ROCK2 (0.45) | — | |
| SCHEMBL10338954 | 0.65 | ALOX5 (0.52) | KDM4EMEN1KMT2ADDB1CRBN | |
| SCHEMBL5223504 | 0.64 | BCHE (0.66) | BCHEKDM4ECYP2D6ALDH1A1 | |
| SCHEMBL10814936 | 0.64 | MAPT (0.60) | ADRB1MEN1KMT2ADDB1CRBN | |
| SCHEMBL20204885 | 0.63 | BCHE (0.36) | BCHEADRB2ADRB1ADRB3KDM4E | |
| SCHEMBL21536616 | 0.63 | DUT (0.45) | KMT2AALDH1A1 | |
| SCHEMBL20204632 | 0.63 | ADRB2 (0.50) | ADRB2ADRB1MEN1KMT2AALDH1A1 | |
| SCHEMBL20204633 | 0.62 | CYP2D6 (0.35) | BCHEADRB2ADRB1ADRB3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018098209-A1 | AMINO SULFONYL COMPOUNDS | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2018-05-31 | — | — | WO | disclosed |