Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTNNB1 | P35222 | 1/20 | 0.40 |
| ▸ | WNT3A | P56704 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 2/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.38 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.38 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | HTR5A | P47898 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3115776 | 0.77 | ALDH1A1 (0.44) | ADRA2AADRA1DADRA1AADRA1BMAPT | |
| SCHEMBL4894342 | 0.75 | GRM5 (0.46) | MAPTALDH1A1 | |
| SCHEMBL30517094 | 0.73 | ALOX5 (0.51) | CTNNB1WNT3AADRA1DADRA1AADRA1B | |
| SCHEMBL984368 | 0.73 | ALOX5 (0.51) | CTNNB1WNT3AADRA1DADRA1AADRA1B | |
| SCHEMBL15202099 | 0.73 | FABP6 (0.40) | ADRA2AADRA1DADRA1AADRA1BMAPT | |
| SCHEMBL5248739 | 0.73 | ITGB2 (0.38) | EGFRADRA2AADRA1DADRA1AADRA1B | |
| SCHEMBL16404623 | 0.73 | MAPT (0.43) | EGFRADRA2AADRA1DADRA1AADRA1B | |
| SCHEMBL20756201 | 0.73 | ADRA2A (0.40) | ADRA2AADRA1DADRA1AADRA1BMAPT | |
| SCHEMBL30641376 | 0.73 | ADRA2A (0.40) | ADRA2AADRA1DADRA1AADRA1BMAPT | |
| SCHEMBL30343091 | 0.73 | ITGB2 (0.38) | ADRA2AADRA1DADRA1AADRA1BMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025091026-A1 | THERAPEUTIC COMPOSITIONS CONTAINING G-CLAMP PNA AND USES THEREOF | UNIVERSITY OF CONNECTICUT (US) | 2025-05-01 | — | — | WO | claimed |
| WO-2025091026-A1 | THERAPEUTIC COMPOSITIONS CONTAINING G-CLAMP PNA AND USES THEREOF | UNIVERSITY OF CONNECTICUT (US) | 2025-05-01 | — | — | WO | disclosed |
| US-20230150978-A1 | QUINAZOLINONE DERIVATIVES AND USES THEREOF FOR TREATING A CANCER | ENYO PHARMA (FR) | 2023-05-18 | — | — | US | disclosed |
| EP-4126847-A1 | QUINAZOLINONE DERIVATIVES AND USES THEREOF FOR TREATING A CANCER | ENYO Pharma (FR) | 2023-02-08 | — | — | EP | disclosed |
| US-11174271-B2 | 6-membered uracil isosteres | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2021-11-16 | — | — | US | disclosed |
| WO-2021198188-A1 | QUINAZOLINONE DERIVATIVES AND USES THEREOF FOR TREATING A CANCER | ENYO PHARMA (FR) | 2021-10-07 | — | — | WO | disclosed |
| US-20190270756-A1 | 6-MEMBERED URACIL ISOSTERES | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2019-09-05 | — | — | US | disclosed |
| WO-2018098204-A1 | 6-MEMBERED URACIL ISOSTERES | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2018-05-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230150978-A1 | QUINAZOLINONE DERIVATIVES AND USES THEREOF FOR TREATING A CANCER | NQO2, NQO1, NDUFV2 | CTNNB1 3127/4885WNT3A 2218/4885EGFR 1930/4885 |
| US-11174271-B2 | 6-membered uracil isosteres | UNG, DUT, DPYD | CTNNB1 2830/4885WNT3A 3687/4885EGFR 3945/4885 |
| US-20190270756-A1 | 6-MEMBERED URACIL ISOSTERES | UNG, DUT, DPYD | CTNNB1 2830/4885WNT3A 3687/4885EGFR 3945/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.